Chu X, Bleasby K, Chan GH, Nunes I and Evers R (2016) The Complexities of Interpreting Reversible Elevated Serum Creatinine Levels in Drug Development: Does a Correlation with Inhibition of Renal Transporters Exist? Drug Metab Dispos.Chu X, Bleasby K, Chan GH, Nunes I, and Evers R (...
utilised assay in the assessment of renal function4. The National Kidney Disease Education Program recommends calculating GFR from SCr. Creatinine measurements are useful in the monitoring of disease progression, with the diagnosis of renal failure when SCr levels are greater than the upper normal ...
Serum cystatin C often is used in humans as a rapid and more sensitive marker than serum creatinine for glomerular filtration rate. The purpose of the pres... Asger,L.,Jensen,... - 《Veterinary Clinical Pathology》 被引量: 71发表: 2001年 Plasma creatinine levels, estimated glomerular filtrati...
We concluded that guanidinoacetate concentration is a parameter to be considered in the follow-up of patients with urea cycle defects, and arginine should be supplemented in sufficient amounts, as the brain seems to be impermeable to creatine influx, but not to its precursor, arginine, which is...
Effect of Oestrogen on Altering the Serum and Urinary Levels of Calcium, Phosphate and Magnesium in Hysterectomised Women Compared to Natural Menopausal So... Given the paucity of studies conducted to know the effect of suddenness and earlier onset of endocrinological changes associated with hysterect...
, 1974). Secretion of creatinine by active transport in the proximal tubule has been reported in humans, in whom it is nonuniformly increased in renal failure (Walser et al., 1988), also in sheep (Bickhardt and Dungelhoef, 1994), rabbit (Matos et al., 1998), pig (Wendt et al., ...
Contact of humans with the earth, either directly (e.g., with bare feet) or using a metal conductor, changes their biochemical parameters. The effects of earthing during physical exercise are unknown. This study was carried out to evaluate selected biochemical parameters in subjects who were eart...
The effect of fibrates and other lipid-lowering drugs on plasma homocysteine levels. The most likely mechanism for this increase is an alteration of creatine-creatinine metabolism and changes in methyl transfer. Gemfibrozil does not increase ... Jutta,Dierkes,Sabine,... - 《Expert Opinion on Drug...
Creatinine (2-Amino-1-methyl-2-imidazolin-4-one) is a product of creatine kinase activity in skeletal muscle. Therefore serum creatinine levels are consistent depending on an individuals muscle amount (1). Serum creatinine is absorbed by the kidneys via glomerular filtration and then excreted...
Frankly abnormal serum creatinine levels will occur in some cases. CERTAIN EFFECTS of the hypothyroid state on the kidney are well established. Histological changes have been demonstrated in both rats1 and humans.2,3 Physiological effects include changes in water and electrolyte metabolism, notably ...