Urine creatinine concentrations as parameter for preanalytical validation of samples in drug monitoring screeningdoi:10.1016/j.cca.2019.03.1575T. González CejudoM.T. De Haro RomeroJ.M. Villa SuárezM.D.M. Maldonado MontoroA. Espuch Oliver...
Creatinine is a waste product in the body that comes from the normal breakdown of muscle tissue and thedigestionof proteins in yourdiet. This waste product is normally removed from the body by the kidneys. It is normal to have creatinine in the bloodstream, but high levels can signal that t...
Creatinine tests are used to measure the level of a waste product, known as creatinine, in your blood and urine. Creatinine is produced during the normal breakdown of muscle tissue, and because it is produced at a relatively steady rate, labs can use it as a marker to see how well your ...
urine protein to creatinine ratio; bevacizumab; angiogenesis inhibitors; antineoplastic agents; proteinuria; albuminuria Graphical Abstract1. Introduction Bevacizumab has been approved by the U.S. Food and Drug Administration (FDA) for the treatment of malignant neoplasms, particularly as first-line ...
A 24-hour urine protein may be ordered as a follow-up test, especially in pregnant women with a high pre-screen risk of preeclampsia, when the dipstick test shows there is a large quantity of protein present in the urine or when protein is shown to be persistently present. ...
The role of the difference and ratio of albuminuria (urine albumin-to-creatinine ratio, uACR) and proteinuria (urine protein-to-creatinine ratio, uPCR) has not been systematically evaluated with all-cause mortality. We retrospectively analyzed 2904 patie
Method validation results showed reproducibility with within-run precision of 3.59, 3.49 and 2.84% and between-run precision of 4.01, 3.28 and 3.57% for low, medium and high quality control materials prepared from pooled donor urine, respectively. The method showed excellent accuracy with a bias ...
Study drug dose rationale15 is explained in eMethods 4 in Supplement 3. The lowest dose was chosen with predicted trough plasma concentrations below the assumed effective concentration. The middle and high doses were chosen based on trough concentrations reaching or exceeding, respectively, the ...
Future concepts of drug screen in urine should use gender-specific and creatinine-adjusted decision limits.doi:10.1016/j.forsciint.2009.01.010T. ArndtElsevier Ireland LtdForensic Science InternationalArndt T (2009) Urine-creatinine concentration as a marker of urine dilution: reflections using a ...
A double-sided multi-channel screen-printed electrode (SPE) was designed for the purpose of detecting creatinine, uric acid, and pH in urine. The electrochemical sensor was fabricated on a polyimide (PI) substrate using a multi-layer screen printing technique. One side of the sensing electrode ...