An insurance handling issue with both serum creatinine and any eGFR calculation based on it is the variable time delay and holding temperature before centrifugation (separating the serum from red and white blood cells) of the blood sample. This can sometimes be hours at room temperature...
The current equation that uses both markers (eGFRcr-cys) is more accurate than either eGFRcr or eGFRcys. This calculation, originally published by Dr. Inker in the New England Journal of Medicine, uses creatinine and cystatin C to estimate kidney function without using race. It has been ...
The MDRD equation, used to calculate "eGFR", was originally developed using a conventional serum creatinine assay and later was republished using IDMS-based values. The update to MDRD, called the CKD-EPI equation, exclusively relies on IDMS-based values only....
(e.g., obstruction or extravasation of urine into the peritoneal cavity) may falsely elevate serum concentrations in the absence of parenchymal damage. Thus, a decrease in the eGFR inferred from an increase in the serum creatinine level may not distinguish among prerenal, intrinsic renal, and ...
calculation of the glomerular filtration rate is used to identify at-risk patients. The possible methods for measuring renal function using laboratory tests and the various equations for estimating glomerular filtration rate are reviewed, and questionnaires to replace serum creatinine measurement in ...
developed an alternative to this formula that was indexed to body surface area. In its original form, it used six measurements to estimate GFR (eGFR), including blood urea nitrogen and albumin levels. A basic four-variable form of the calculation containing serum creatinine, age, race and ...
glomerular filtration rate (eGFR) [75– 100 ml/min / 1.73 m2], that was useful for defining the value of bSCr using the Modification of Diet in Renal Dis- ease (MDRD) equation (back‐estimation) in patients with unknown baseline renal function and in the absence of prior renal disease [...
Characteristics of the 26 participants who provided all six urine samples are summarized in Table 1: 89 % were men and 77 % Caucasian, and the average age was 63 years (SD 14); 89 % had hypertension and 69 % had diabetes. Average eGFR at baseline was 36 ml/min/1.73 m2 (SD 15). ...
In the present study, UNAPCR ≥ 120 mg/g and eGFR < 60 mL/min/1.73 m2 but not UACR were found to be independent predictors of all-cause mortality. Even though patients presented normoalbuminuria (UACR < 30 mg/g), the mortality risk still increased if patients concurrently ...
A mathematical calculation of the total amount of creatinine excreted in the urine over a period of time, usually 24 hours to test renal function. The calculation is: creatinine clearance (mL/minute) = urine creatinine concentration (mL/dL) × volume of urine (mL/24 hour) ÷ plasma creatinin...