Although focus on NF-kB has been primarily on cancer and inflammation, it plays integral roles in memory and synaptic function [80]. NFk-B has been shown to target neurons and negatively affect APP and Aβ aggregation in AD [80]. Cr supplementation in rodents has been shown to decrease ...
Further studies show that many metabolites are involved in manipulating cell signaling, such as mTOR, MAPK, and NF-kB (Deldicque et al., 2007; Elia et al., 2018; Pazini et al., 2016). However, owing to technological barriers, the mechanism of modification and regulation of specific genes...
Among them, several hub proteins such as NFKB1, FHL2, MYOC, and ASB9 were predicted. Determination of the binding factors of CK can further promote our understanding of the roles of CK in physiological conditions.Wei-JiangZhejiangHuZhejiang...
Hundreds of genes, including muscle creatine kinase (MCK), are differentially expressed in fast- and slow-twitch muscle fibers, but the fiber type-specific regulatory mechanisms are not well understood. Modulatory region 1 (MR1) is a 1-kb regulatory regi
Anti-rabbit Phospho-NF-κB p65 (Ser536) Cell Signaling Technology Cat#3033; RRID: AB_331284 Anti-rabbit Phospho-4E-BP1 (Thr37/Thr46) Cell Signaling Technology Cat#2855; RRID: AB_560835 Anti-mouse β-Tubulin EASYBIO Cat#BE0025 Anti-mouse CD4 BioLegend Cat#100405; RRID: AB_312690 Anti-mo...
Increased NF-kappaB signalling up-regulates BACE1 expression and its therapeutic potential in Alzheimer’s disease. Int. J. Neuropsychopharmacol. 2012, 15, 77–90. [Google Scholar] Ferrer, I.; Marti, E.; Lopez, E.; Tortosa, A. NF-kB immunoreactivity is observed in association with beta A4...