The meaning of CREATINE KINASE is any of three isoenzymes found especially in vertebrate skeletal and myocardial muscle that catalyze the transfer of a high-energy phosphate group from phosphocreatine to ADP with the formation of ATP and creatine.
Background Creatine kinase (CK) is an enzyme found in skeletal muscles, myocardium and brain (CK–MM, CK–MB, and CK–BB isoenzymes respectively). In these tissues with high energy requirements, CK catalyses conversion of phosphocreatine to creatine, generating adenosine triphosphate. Elevated CK...
Elevated levels of CK-MB indicate that the muscles cells in the heart have been damaged. If the total CK level is high but the levels of CK-MB are low, this usually indicates that another muscle has been injured, while a high ratio of CK-MB: total CK indicates that the heart has bee...
Logistic regression test: Elevated CK is an independent risk factor. 多因素分析:血清肌酸激酶升高为独立危险因素。 —— 给力词典精选 3. Creatine kinase increase after intravenous infusion of vancomycin hydrochloride 静脉滴注稳可信导致血肌酸激酶升高 ...
Creatine Kinase Creatine kinaseis a minimally useful tool in evaluating a suspected congenitalmyopathy. It may be mildly elevated or it may be normal. A creatine kinase value greater than two times normal should suggest an alternative diagnosis. ...
We report serum creatine kinase (CK) activity level in patients with Parkinson's disease and controls matched with gender and age. The clinical subjects consist of 84 patients with Parkinson's disease and 257 control subjects. Serum CK level was significantly elevated in parkinsonian patients (117.3...
In general, elevated CK occurs in the initial stage of neuroleptic malignant syndrome and corresponds temporally with the onset of muscle rigidity. However, in some exceptional cases, CK elevation and emergence of muscle rigidity do not appear in the same stage, making early diagnosis of ...
Creatine Kinase is a dimeric enzyme composed of M and/or B subunits which associate to form the CK-MM, CK-MB and CK-BB isoenzymes.1,2Following myocardial infarction the CK-MM level rises and reaches a peak between 18-30 hrs, the increase being similar to that of the total CKactivity....
Testing is performed when the total Human Creatine Phosphokinase (CPK) level is elevated. Isoenzyme testing can help differentiate the source of the damaged tissue. Human CPK enzyme consists of two subunits, which can be either B (brain type) or M (muscle type). Three different isoenzymes: ...
A creatine kinase-MB (CK-MB) test may be used as a follow-up test to an elevated creatine kinase (CK) in order to determine whether the increase is due to heart damage or skeletal muscle damage. The test is most likely to be ordered if a person has chest pain or if a person’s ...