Objective To determine whether serum creatine kinase activity (CK) and serum creatinine concentration (Crn) are prognostic and predictive biomarkers for disease severity, disease progression, and nusinersen treatment effects in adult patients with 5q鈥恆ssociated spinal muscular atrophy (SMA). Methods ...
Related to creatine kinase (CK):Creatine Kinase Test cre·a·tine (krē′ə-tēn′, -tĭn)alsocre·a·tin(-tĭn) n. A compound, C4H9N3O2, that is found in the muscle tissue of vertebrates mainly in the form of phosphocreatine and that is involved in the storing and supplying ener...
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creatine kinaseAlso found in: Dictionary, Thesaurus, Financial, Acronyms, Encyclopedia, Wikipedia. Related to creatine kinase: creatinine, Creatine Kinase Testcreatine [kre´ah-tin] a nonprotein substance synthesized in the body from three amino acids: arginine, glycine (aminoacetic acid), and ...
BACKGROUND: The creatine kinase system, the central regulatory system of cellular energy metabolism, provides ATP in situ at ATP-ases involved in ion transport and muscle contraction. Furthermore, the enzyme system provides relative protection from tissue ischaemia and acidosis. The system could theref...
Very recently, a series of new discoveries have been made that are bound to have distinguished implications for bioenergetics, physiology, human pathology, and clinical diagnosis and that suggest that deregulation of the creatine kinase (CK) system is associated with a variety of diseases. ...
来自 国家科技图书文献中心 喜欢 0 阅读量: 27 作者: Lee,E.,McDermott,C.,J.,Bradburn,M.,Rafiq,M.,K. 摘要: Background and purpose: Amyotrophic lateral sclero 关键词: amyotrophic lateral sclerosis biomarker creatine kinase creatinine muscle mass 年份: 2016 ...
Creatine Kinase CKis anenzymethat catalyzes the conversion ofphosphocreatine, the energy reservoir for regeneration of ATP, degrading ATP to ADP. CK consists of two subunits, a muscle-type M and a brain-type B. CK consists of threeisoenzymes: CK-MM in skeletal muscle, CK-BB in brain, and...
Related to creatine:creatinine Category filter: AcronymDefinition CREACreative CREACanadian Real Estate Association CREACommercial Real Estate Association(various locations) CREACreatine CREAConselho Regional de Engenharia, Arquitetura E Agronomia(Regional Engineering, Architecture and Agronomy Council - Brazil) ...
the isoenzymes of creatine kinase. Creatine kinase is a dimer with M (muscle) and/or B (brain) subunits; it exists in three isoenzyme forms: CK-MM, the predominant form, found primarily in skeletal muscle; CK-MB, found in cardiac muscle, tongue, diaphragm, and in small amounts in skel...