the intense compounds in skunk spray can result in oxidative damage to red blood cells, leading to changes in their ability to transport oxygen appropriately as well as death of the cell,” explained Renee Schmid, DVM, DABT, DABVT, a senior veterinary toxicologist and director of veterinary med...
Of the 6 questions that tested knowledge, three differed significantly between clinicians and patients (Table): on a seven-category Likert scale, clinicians felt more knowledgeable than patients about the hemoglobin level at which red blood cells should be transfused (5.5 vs 2.1; p<0.0001), ...
The name of the disease comes from the "sickle" shape of thered blood cellsthat form in patients with the disorder. Red blood cells contain the protein hemoglobin, which carries oxygen in the blood. People with sickle cell disease have amutated genethat codes for abnormal hemoglobin, which af...
Sugar attaches to a protein in red blood cells that carries oxygen to organs and tissue and that transports carbon dioxide to the lungs. The A1C test measures the average percentage of glucose in a person's hemoglobin over the span of several months. Healthy A1C levels are below 5.7%. Gener...
The red lines delineate tumours. g, Immunofluorescence images of orthotopic model-derived tumour samples stained with nestin. h, Proportion of cells in g that were nestin+; three fields per sample. d,h, The data represent the mean ± s.e.m. of n = 3 biologically independent ...
Loss of Stim1 function in mice and humans is associated with antibody-mediated autoimmunity due to defects in T lymphocyte helper function to B cells. We investigated autoantibody formation using a high-density protein array to detect the presence of IgG and IgM autoantibodies in SHR-A3. ...
A major friction point for aerobic development is the transportation of oxygen-rich red blood cells to working muscles via capillaries. Running induces angiogenesis, or increased capillarization. Studies on mice involving deep muscle biopsies show that the adaptations can happen with...
In prior work, we found that PB causes acute immunosuppression in the colon and brain that potentially involves T lymphocytes, mast cells, and monocytes (Hernandez et al., 2019). Interestingly, these immunosuppressive effects appear to persist in the brain of male mice up to 5 months following...
cells for KCNE3 lentivirus infected dish and red cells for KCNE4 lentivirus infected dish (when viewed under fluorescence microscope) were used for patch-clamp recordings. IKscurrents were elicited by holding cells at −40 mV and then depolarized from −40 to +50 mV in the interval ...
Here we present a compendium of single-cell transcriptomic data from the model organism Mus musculus that comprises more than 100,000 cells from 20 organs and tissues. These data represent a new resource for cell biology, reveal gene expression in poorly