CAS:2429878-72-6 分子式:C21H22N2O5 分子量:382.41 物化属性 化工字典合成路线 化合物别名 英文名称 7-Octynoic acid, 8-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-1H-isoindol-4-yl]- 英文别名 Lenalidomide-acetylene-C5-COOH; Cereblon ligand-linker Conjugate; Acide 8-[2-(2,6-dio; ...
结构式: 产品简介:4-氟沙利度 胺是用于补充CRBN蛋白的沙利度 胺基脑啡肽配体。它可以通过连接子连接到IRAK4蛋白的配体,形成PROTAC IRAK4降解物-1(HY-129966)。 小分子PEG是指PEG以2个或2个以上的重复单元相连接而成,他们不同于高分子PEG,他们的分子量都是固定值,而分子量的大小跟重复单元相关,重复单元越高...
Using apoptosis model and combination analyses, we found that pomalidomide directly targeted ETFA, and increased ATP generation, thereby significantly promoting tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis. Specific knockdown of ETFA could effectively eliminate the ...