Tumor cell energy metabolism and its common features with yeast metabolism R. Diaz-Ruiz, ... M. Rigoulet, in Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2009 Recently, we showed that there is a link between glycolysis and the Crabtree effect. One of the intermediates of this...
1966. The Crabtree effect: a regulatory system in yeast. J Gen Microbiol. 44:149-156.De Deken RH (1966) The Crabtree effect: a regulatory system in yeast. J Gen Microbiol 44:149-156De Deken R. The Crabtree effect: a regulatory system in yeast. J Gen Microbiol. 1966;44(2):149-56....
Revisiting the Crabtree/Warburg effect in a dynamic perspective: a fitness advantage against sugar-induced cell death Cell Cycle, 17 (2018), pp. 688-701 Google Scholar Denoon et al., 2020 T. Denoon, S. Sunilkumar, S.M. Ford Acetoacetate enhances oxidative metabolism and response to toxicant...
©2010ElsevierB.V.Allrightsreserved.1.Thehallmarksofcancercellenergymetabolism:TheWarburgeffectandtheCrabtreeeffectInordertoproliferate,cellsmustcomplywiththeenergydemandimposedbyvitalprocessessuchasmacromoleculebiosynthesis,DNAreplication,iongradientsgenerationandcellstructuremaintenance.Mitochondriaplayanimportantrolein...
Mitochondrial physiology in cancer cells is linked to the Warburg effect. Besides, its central role in apoptosis makes this organelle a promising "dual hit target" to selectively eliminate tumor cells. From a metabolic point of view, the fermenting yeast Saccharomyces cerevisiae and tumor cells ...
due to the ability to rapidly consume glucose and produce ethanol that has antiseptic properties. However, it generally results in reduced yields when this yeast is used as a cell factory. There is therefore much interest in rewiring the central carbon metabolism to abolish the Crabtree effect. ...
The short-term Crabtree effect is defined as the immediate occurrence of aerobic alcoholic fermentation in response to provision of a pulse of excess sugar to sugar-limited yeast cultures. Here we have characterized ten yeast species with a clearly defined phylogenetic relationship. Yeast s...
Yeast short-term Crabtree effect — Growth kinetics for all experiments.Arne, Hagman
There is a correlation between the presence of the Crabtree effect in a yeast strain and its ability to give petite mutants.doi:10.1099/00221287-44-2-157DE DEKENR. H.J Gen MicrobiolDe Deken, R. H. (1966b) The Crabtree effect and its relation to the petite mutation. J. Gen. Microbiol...
and R(Smt, M. 1981. Evaluation of the Crabtree effect in different yeasts grown in batch and continuous culture, p. 405-410. In G. G. Stewart and I. Russell (eds), Current Developments in Yeast Research. Pergamon Press, Toronto.