The NDA is supported by data from 18 clinical trials, including two Phase 3 trials that evaluated paltusotine for the treatment of acromegaly in medically untreated and treated patients. All primary and secondary endpoints were met in both Phase 3 studies....
Crinetics Pharmaceuticals is a clinical stage pharmaceutical company focused on the discovery, development, and commercialization of novel therapeutics for endocrine diseases and endocrine-related tumors.Paltusotine, an investigational, first-in-class, oral somatostatin receptor type 2 (SST2) agonist, is ...
The NDA is supported by data from 18 clinical trials, including two Phase 3 trials that evaluated paltusotine for the treatment of acromegaly in medically untreated and treated patients. All primary and secondary endpoints were met in both Phase 3 studies. Treatment with paltusotine was well-toler...
Clinical Trials Acromegaly in a Pandemic Acromegaly Symptoms Acromegaly Diagnosis Acromegaly Advocate Acromegaly Support Professionals Acromegaly Carcinoid Syndrome Investors Overview Corporate Presentation SEC Filings Stock Information Corporate Governance Press Releases Events & Presentations ...
the success of Crinetics’ clinical trials and nonclinical studies; regulatory developments in the United States and foreign countries; Crinetics may use its capital resources sooner than it expects; and the other risks and uncertainties described in the company’s periodic filings with the SEC. ...
In clinical trials, patients with moderate to severe motor fluctuations who received SINEMET CR did not experience quantitatively significant reductions in 'off' time when compared to SINEMET. However, global ratings of improvement as assessed by both patient and physician were better during therapy wit...
其次BD的问题。B中说在新drug拿到patent之后，进行Clinical trials 需要十年，次才能投入市场赚钱，所以20...
“Crinetics made significant progress in 2019 advancing our development programs, as highlighted by the initiation of the ACROBAT Phase 2 clinical trials for acromegaly with our lead product candidate paltusotine,” saidScott Struthers, Ph.D., Founder and Chief Executive Officer of Crin...
STP705 is being investigated in multiple clinical trials including a phase 1/2 trial [NCT04293679] for cutaneous squamous cell carcinoma in situ [isSCC], where it demonstrated strong efficacy with 19 out of 25 patients showing complete histological clearance.3Another trial (NCT05421013) is investig...
[10] JONES J, MATO A, COUTRE S, et al. Evaluation of 230 patients with relapsed/refractory deletion 17p chronic lymphocytic leukaemia treated with ibrutinib from 3 clinical trials [J]. Br J Haematol, 2018, 182(4): 504-12. [11] BYRD J C, WOYACH J A, FURMAN R R, et al. Final...