38 A previous study also found that targeting CPT1A with etomoxir impeded the progression of MYC-driven triple-negative breast cancer.14 In addition to the accumulation of antioxidants, such as NADPH or GSH, we found that CPT1A could upregulate GPX4 expression and decrease PUFA-PLs levels to ...
KAT3B-p300 is a critical regulator of hematopoiesis, and its heightened expression is recurrent in human malignancies such as prostate [44], liver [12, 45], and breast cancer and is predictive of worse prognosis. Accordingly, the activation of several oncogenes which directly sustain cancer ...