Potent therapeutic activity of irinotecan (CPT-11) and its schedule dependency in medulloblastoma xenografts in nude mice. Int. J. Cancer, 73: 156 -163, 1997.Vassal G, Boland I, Santos A, Bissery M, Terrier-Lacombe M, Morizet J, Sainte-Rose C, Lellouch-Tubiana A, Kalifa C, Go...
97124-Therapeutic Procedure, 15 minutes. One or more areas, including effleruage, pettrissage and/or tapotement, compression, percussion. 97140– Therapeutic Procedure, 15 minutes. Mobilization, manipulation, manual lymphatic drainage, manual traction, one or more regions. 97122– Therapeutic Procedure,...
humidification therapy(humidity therapy) the therapeutic use of air supersaturated with water to prevent or correct a moisture deficit in the respiratory tract; see alsohumidity therapy. immunosuppressive therapytherapeuticimmunosuppression. inhalation therapythe term formerly used forrespiratory care(def. 3)...
CPT-11 is a camptothecin derivative with a broad spectrum of antitumor activity, both in vitro and in vivo. Like camptothecin, CPT-11 is a selective DNA topoisomerase I inhibitor. Phase I trials were conducted in Europe to determine the dose and schedule for phase II trials. These phase I ...
17.A Mechanistic, Multiscale Mathematical Model of Immunogenicity for Therapeutic Proteins: Part 1—Theoretical Model 机译:治疗性蛋白质免疫原性的机械化,多尺度数学模型:第1部分-理论模型 作者:TP Hickling;X Chen 期刊名称:《CPT: Pharmacometrics & Systems Pharmacology》 | 2014年第9期 18.Incorporating ...
Background and purpose: α/β-hydrolase domain containing 6 (ABHD6), a new member of the endocannabinoid system, is a promising therapeutic target against neuronal-related diseases. However, regulatory players in ABHD6 activity are not known. ABHD6 co-exists in protein complexes with the brain...
Multiomic analysis identifies CPT1A as a potential therapeutic target in platinum-refractory, high-grade serous ovarian cancer. Cell Rep. Med. 2, 100471 (2021). Article CAS PubMed PubMed Central Google Scholar Luo, M. et al. Overexpression of carnitine palmitoyltransferase 1A promotes ...
In vivo treatment of the t(11;17) APL mouse model demonstrated that 8-CPT-cAMP could significantly improve the therapeutic effect of ATRA by targeting a leukemia-initiating cell activity. This combined therapy, which induces enhanced differentiation and oncoprotein degradation, may benefit t(11;17)...
Human mesenchymal stem cells (hMSCs) are widely used in regenerative medicine. In some applications, they must survive under low nutrient conditions engendered by avascularity. Strategies to improve hMSCs survival may be of high relevance in tissue engin
This new and integrated vision of CPT1C function can help better understand the metabolic plasticity of cancer cells and improve the design of therapeutic strategies. 单位 南方医科大学 全文 全文 访问全文 收藏 分享 被引 浏览 更新时间:2024-12-27 21:32 相似论文 引用论文 参考文献...