Theoretical optimization of Irinotecan-based anticancer strategies in the case of drug-induced efflux concern lies in the design of CPT11-based therapeutic strategies which eradicate a maximum number of cancer cells despite their ability to become resistant... A Ballesta,J Clairambault,S Dulong,.....
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1. (S)-10-Hydroxycamptothecin is the natural starting material of Irinotecan HCl. 2. (S)-10-Hydroxycamptothecin is the natural starting ingredient of 7-Ethyl-10-Hydroxycamptothecin(SN-38). 3. (S)-10-Hydroxycamptothecin is the natural starting ingredient of Topotecan HCl 4. This compound 10-hyd...