The most common adverse reactions (≥20%) were fatigue, decreased appetite, and dyspnea. Adverse reactions occurring in patients with HNSCC were generally similar to those occurring in patients with melanoma or ...
Patients with pirfenidone: 16 had no previous treatment; the mean FVC initial and final value was 72.7% and 79% respectively; one patient needed a dose reduction to control side effects; three patients suffered an exacerbation since pirfenidone initiation; most frequent adverse events were dyspnea ...