The 9 animals in the vaccine group had previously received two intramuscular injections of a DNA plasmid encoding spike protein that had failed to induce detectable serum spike-binding IgG. The active immunization group received two intramuscular injections 10 days apart of recombinant CoV-2-S-ΔTM...
In total, 311 participants were randomized to the SpikoGen® group and 89 participants to the placebo group. Screening and randomization process of the participants are provided in the CONSORT diagram in Fig. 1. Demographic data and past medical history of the participants are presented in Table...