Presents information on a study which discussed the utilization of Th-1 T-cells to block the development of asthma in children using the murine model. Methods; Results; Conclusions.Russell HoppAmerican Academy of Pediatrics (AAP)PEDIATRICSHopp Russell.Modulation of airway inflammation by CpG ...
As wheezing is a common presentation in children with respiratory airway obstruction, many other diseases such as tracheomalacia , bronchiolitis obliterans may be treated as asthma. Differential diagnosis of asthma were discussed in this guideline particularly the common conditions. A comprehensive ...
DNA methylation in nasal epithelium, atopy, and atopic asthma in children: a genome-wide study. Lancet Respir. Med 7, 336–346 (2019). Article CAS PubMed Google Scholar Cardenas, A. et al. The nasal methylome as a biomarker of asthma and airway inflammation in children. Nat. Commun. ...
Iran J Allergy Asthma Immunol. 2011;10(2):129–32. https://doi.org/10.1002/ijaai.129132. Article CAS PubMed Google Scholar Schroder C, et al. Evaluation of RAG1 mutations in an adult with combined immunodeficiency and progressive multifocal leukoencephalopathy. Clin Immunol. 2017;179:1–7...
Long Term Prevention of Allergic Lung Inflammation in a Mouse Model of Asthma by CpG Oligodeoxynucleotides Asthma is an inflammatory disease of the airways that is induced by Th2 cytokines and inhibited by Th1 cytokines. Despite a steady increase in the incidenc... S Sur,JS Wild,BK Choudhury...
As wheezing is a common presentation in children with respiratory airway obstruction, many other diseases such as tracheomalacia , bronchiolitis obliterans may be treated as asthma. Differential diagnosis of asthma were discussed in this guideline particularly the common conditions. A comprehensive ...
Methylation of the ACSL3 5′-CGI was found to be significantly associated with maternal airborne PAH exposure exceeding 2.41 ng/m 3 (OR=13.8; p <0.001; sensitivity=75%; specificity=82%) and with a parental report of asthma symptoms in children prior to age 5 (OR=3.9; p <0.05). Thus...
Asthma is a heterogeneous disorder that is characterized by variable airflow obstruction, airway inflammation and hyperresponsiveness, and reversibility either spontaneously or as a result of treatment. Multiple causes no doubt exist for both its inception and symptom exacerbation once the disease is ...
Some of the detrimental effects may be due to epigenetic modifications, although few studies have investigated this hypothesis in detail.To characterize site-specific epigenetic modifications conferred by prenatal smoking exposure within asthmatic children.Using Illumina HumanMethylation27 microarrays, we ...
Childhood allergic diseases, including asthma, rhinitis and eczema, are prevalent conditions that share strong genetic and environmental components. Diagnosis relies on clinical history and measurements of allergen-specific IgE. We hypothesize that a multi-omics model could accurately diagnose childhood ...