LOOD banks are changing the preservaB tive in liquid bank blood from acid citrate-dextrose ( ACD) to citrate-phosphatedextrose (CPD) solution. Both preservatives contain citric acid, sodium citrate, and dextrose. CPD solution, however, consists of 20 percent less citrate than ACD solution and ha...
but values for both ATP and 2,3-DPG were higher in phosphate treated aliquots than in controls throughout storage. When the pH of blood stored at 4 C was adjusted into the range 7.15 to 7.25 with tromethamine and the level of iP raised to 10 mM by addition of Na 2 HPO 4 on day ...
In-vitro studies show CPD-preserved bank blood to have certain advantages over ACD-preserved blood. In addition to increased length of storage, the higher pH of CPD blood improves the 2,3-DPG level, thereby increasing oxygen release to the tissues in cases where this may be a critical factor...
Factors I and X were not significantly altered during the collection of bank blood into ACD-A and CPD preservative fluids. The factors remained relatively stable on subsequent storage under standard conditions for up to 21 days.doi:10.1111/j.1423-0410.1973.tb02657.xO. Weisert...
Preservation of coagulation factors V and VIII during collection and subsequent storage of bank blood in ACD-A and CPD solutions. Vox Sang 1973;24:126-33.Weisert O., Jeremic M. (1973). Preservation of coagulation factors V and VIII during collection and subsequent storage of bank blood in...