“The rush to create a COVID-19 vaccine may do more harm than good” (Torreele2020). The article lamented the fact that a vaccine may only provide short term protection or may offer only low vaccine effectiveness (less than 50%). The article quotes Phil Krause, then deputy...
There are some limitations to our study. First, both natural infection and vaccination have been shown to drive distinct IgG Fc profiles90. Thus, specific vaccine platforms (for example, adenoviruses, messenger RNA, adjuvanted nanoparticles) are likely to drive distinct Fc subclass/isotype/glycosylatio...
This type of COVID-19 vaccine has harmless S proteins. The immune system recognizes S proteins and creates antibodies and defensive white blood cells to fight the viral agent (e.g., the vaccine developed by Novavax, an American biotechnology company; cf., GAVI, 2021; readings Coccia, 2005,...
Step 2 Phase I Safety Trials vaccine is given to a small number of people to test safety and dosage as well as to confirm that it stimulates the immune system Step 3 PHASE II Expanded Trials Vaccine is given to hundreds of people including children and adults to see if it acts differently...
It was urgent and necessary to synthesize the evidence for vaccine effectiveness (VE) against SARS-CoV-2 variants of concern (VOC). We conducted a systematic review and meta-analysis to provide a comprehensive overview of the effectiveness profile of COV
(1) Background: Canada had a unique approach to COVID-19 vaccine policy making. The objective of this study was to understand the evolution of COVID-19 vaccination policies in Ontario, Canada, using the policy triangle framework. (2) Methods: We searched government web...
Accessed June 20, 2023. https://covid19-sciencetable.ca/sciencebrief/covid-19-vaccine-confidence-in-ontario-and-strategies-to-support-capability-opportunity-and-motivation-among-at-risk-populations/ 32. Warren M, Wallace K. Vaccination trend for Ontario kids 5-11 ‘alarming.’ Toronto ...
The present study examined willingness to receive a COVID-19 vaccine, the associated reasons for willingness/unwillingness, and vaccine safety perceptions in a cross-sectional assessment of community adults in Ontario. Methods: One thousand three hundred sixty seven individuals (60.6% female, mean age...
Submission deadline 01 August 2023 The novel coronavirus SARS-CoV-2 has precipitated the present outbreak of COVID-19, a highly infectious respiratory disease. This Collection brings together advances in the tools researchers are developing to combat this pandemic – from methods of detection, to po...
SARS-CoV-2 infection poses increased risks of poor outcomes during pregnancy, including preterm birth and stillbirth. There is also developing concern over the effects of SARS-CoV-2 infection on the placenta, and these effects seem to vary between differ