In the absence of these confounders, we take an experimental medicine approach to examine the in vivo utility of remdesivir. Over two independent courses of treatment, we observe a temporally correlated clinical and virological response, leading to clinical resolution and viral clearance, with no ...
- treatment with remdesivir (hazard ratio, 1.95; 95%CI, 0.86～4.44) Results-safety No new safety signal for tocilizumab emerged. Neutropenia developed in 22 patients in the tocilizumab group, as compared with only 1 patient in th...
In 2021, COVID-19 treatment remdesivir dominated hospital drug spending, accounting for nearly 10% of all pharmaceutical expenses. Clinic and hospital drug spending increased due to higher usage and new drugs; price increases remained below inflation. TheCOVID-19treatment remdesivirdominated hospital dr...
Remdesivir for the treatment of COVID-19: A systematic review and meta-analysis of randomized controlled trials - ScienceDirectCOVID-19RemdesivirSARS-Cov-2Background: The nucleotide analogue prodrug remdesivir was among the first antiviral therapies to be tested in randomized controlled trials (RCTs)...
1. Beigel JH, Tomashek KM, Dodd LE, et al. Remdesivir for the Treatment of Covid-19 - Final Report. N Engl J Med 2020;383(19):1813-1826 2. Wang Y, Zhang D, Du G, et al. Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre tr...
Remdesivir: an antiviral for the treatment of COVID‐19The antiviral remdesivir (Veklury) is the first drug to be licensed for the treatment of COVID. This article discusses its mode of action, indications, clinical trial efficacy and side〆ffects.doi:10.1002/psb.1859...
美国fda紧急批准瑞德西韦(remdesivir)用于治疗covid-19
摘要: This living systematic review aims to provide a timely, rigorous and continuously updated summary of the evidence available on the role of remdesivir in the treatment of patients with COVID-19. PROSPERO RegistrationCRD42020183384DOI: 10.31219/osf.io/zwqf2 年份: 2020 ...
100.de Wit,E.; Feldmann,F.; Cronin,J.; Jordan,R.; Okumura,A.; Thomas,T.; Scott,D.; Cihlar,T.; Feldmann,H.Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.Proc.Natl.Acad.Sci...
The central government will soon approve the use of the drug remdesivir as a treatment for COVID-19 in Japan, a promising development in the battle to end the novel coronavirus pandemic. “Pharmaceutical approval is expected to be possible soon” Prime Minister Shinzo Abe said at the Lower Hou...