However, the restriction was cancelled on 8 May 2020, after concerns were raised about the exacerbation of symptoms by delayed diagnosis, and when the influenza season was recognized as over18,19. Around the same time, remdesivir (an antiviral drug that is an RNA polymerase inhibitor, recognized...
F.M.L. is a full-time employee of Roivant. Roivant is developing gimsilumab, a mAb to GM-CSF under investigation in a phase II clinical trial for the treatment of patients with COVID-19 with lung injury or ARDS. J.R.T., B.B. and J.A.H have received consulting fees from Roi...
COVID-19 The Diagnosis and Treatment Protocol for COVID-19 in China was used to determine COVID-19 severity: 1) for mild cases, the clinical symptoms were minimal, and there was no sign of pneumonia CT image; 2) for moderate cases, the patients only had a fever and respiratory symptoms...
In particular, our COVID-19 unit consisted of 28 beds dedicated to low-intensity and sub-intensive care. The demographic characteristics of the patients, all their comorbidities, their COVID-19 signs and symptoms, their clinical presentation and laboratory findings on admission, their need for ...
The model includes compartments of three diseases: COVID-19, tuberculosis, and diabetes. TB and diabetes were selected in this model because of the significant impact of the COVID-19 pandemic on TB medical treatment and diabetes progression, especially during the implementation of quarantine and ...
Clinical Information Clinical information for the 5 patients before and after convalescent plasma transfusion was obtained from a review of the hospital computer medical system and included the following: demographic data, days of admission from symptom onset, and presenting symptoms; data about various ...
Symptoms and symptom clusters associated with SARS-CoV-2 infection in community-based populations: results from a statewide epidemiological study. medRxiv. Preprint updated October 22, 2020. doi:10.1101/2020.10.11.20210922Google Scholar 30. Garibaldi BT, Fiksel J, Muschelli J, et ...
This longitudinal study surveyed the general population twice - during the initial outbreak, and the epidemic's peak four weeks later, surveying demographics, symptoms, knowledge, concerns, and precautionary measures against COVID-19. There were 1738 respondents from 190 Chinese cities (1210 first-...
In December 2019, a new disease with pneumonia-like symptoms was spreading throughout Wuhan in China which was entitled as novel coronavirus disease or COVID -19 caused by the virus SARS CoV-2. Within a span of a few days, this disease became a global threat and was termed as a pandemic...
Intriguingly, a distinct phenotype was observed in severe and critical COVID-19 patients, consisting of a significantly compromised type I IFN response characterized by no IFN-β and low IFN-α production and activity [9]. By comparison, in nonhospitalized patients with mild flu symptoms, type ...