(median 0.100%).Assuming that a new COVID-19 epidemic outbreak would start in March or April of 2023,induced by a slightly more infectious mutant strain,we predicted a possible large rebound between September and October 2023,with a peak demand of between 800,000 and 900,000 inpatient beds....
It was clear, by the fall of 2020, COVID-19 vaccines could reduce symptomatic COVID-19 and also severe disease against prevailing strain(s) in adults. This finding will be remembered as a seminal moment in medical history, and two of these products rapidly received emergency use authorization...
Since emerging of coronavirus disease 2019 (COVID-19) caused by a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in December 2019, more than 452 million cases and 6.0 million deaths have been documented worldwide as of 12 March 2022 [1]. COVID-19 vaccines have been ra...
An epidemic of acute respiratory infections caused by a new strain of Coronavirus (COVID-19) appeared in December 2019. On 31 January 2020, the World Health Organization (WHO) announced a worldwide health emergency. Facing the challenging situation of the epidemic, the governments of other countr...
The healthcare systems come under strain during pandemics, especially the capacity at hospitals [12]. According to [13], existing health inequalities in countries due to insufficient health capacity can affect the vulnerable people. We therefore expect the increased availability of hospital beds to ...
the overall burden of death and disease after BTI will likely be substantial, will further add to the toll of this pandemic and will represent an additional strain on already overwhelmed health systems. In planning and development of health resources, governments and health systems should take into...
COVID-19 clinical and surveillance data – December 9, 2022 to January 23, 2023, China. https://en.chinacdc.cn/news/latest/202301/W020230126558725888448.pdf (2023). The Wall Street Journal. China’s Covid-19 surge puts strain on medical workers. https://www.wsj.com/articles/chinas-co...
During the COVID-19 viral circulation (January 2020 to December 2022), the HA gene of H3N2 viruses evolved into an independent evolutionary branch belonging to the 3C.2a1b.2a.1 evolutionary branch (Fig. S2B). This showed closer genetic proximity to the 2022 WHO-recommended vaccine strain A/...
In Vitro study with 30 COVID-19 strains from 14 variants, showing stronger efficacy with ivermectin compared to CQ and remdesivir, and relatively homogeneous efficacy with ivermectin regardless of strain/variant, in contrast to results fo.. Mar 252022 Aminpour et al., Computation, doi:10.3390/comp...
10 Several VOC have emerged from the original wild-type strain isolated in Wuhan since the outbreak first began in December 2019, such as Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1), Delta (B.1.617.2), and Omicron (B.1.1.529).9 The Alpha variant was first detected in the UK...