Macroscopically, hypoxic nerve damage leads to mitochondrial swellings in various brain sites, such as cerebral white matters, brainstem, parahippal gyrus, thalamus and sites with high metabolic requirements [130,131,132,133]. Neurons do not readily regenerate; thus, these clinical presentations may...
COVID-19 presents a variety of ethical challenges in a set of arenas, arenas not always considered in past pandemics. These challenges include issues relat
What’s more, long before this study we had good evidence that anything less than a China-style door-welding lockdown wouldn’t do much good. In a2006 paper, the WHO Writing Group affirmed that “mandatory case reporting and isolating patients during the influenza pandemic of 1918 did not s...
distribution and administration requirements, including risks related to storage and handling after delivery by Pfizer; the risk that we may not be able to successfully develop other vaccine formulations, booster doses or potential future annual boosters or re-vaccinations or new ...
A decision has also been made for tickets to be sold “exclusively to spectators residing in China’s mainland, who meet the requirements of the Covid-19 countermeasures”, the IOC said, and that specific details were under discussion and would be released publicly in due course. ...
Furthermore, the improved solubility enables higher doses to be explored in the clinic and gives clinicians greater flexibility in terms of dose volume to account for patient-specific coadministration requirements. PF-07304814 (prodrug) preclinical in vitro and in vivo ADME profile...
Border city mayors “urgently ask” feds to drop land border testing requirements More than a dozen mayors from across Canada have written an open letter to the Canadian government, “urgently asking” the feds to drop all testing requirements for fully-vaccinated travellers at the Canada-United ...
Patient-level data underlying this article cannot be shared publicly due to data protection and confidentiality requirements. Public Health Scotland and the Chief Medical Officer for Scotland are the data holders for the data used in this study. Data can be made available to approved researchers for...
Cruise ships will be subject to additional safety requirements when they return including enhanced pre-arrival reporting of COVID-19 risk. All passengers will be required to be fully vaccinated against coronavirus. "On the basis of medical advice and with the agreement of National Cabinet, lifting...
In Australia, specific measures have included closures of state borders, staying at home where possible, restriction on the size of outdoor and indoor assemblies, minimum space requirements for each person in enclosed areas, and the requirement to keep a 1.5-metre distance from others [3,4,5]...