The FDA revised the Moderna COVID-19 Vaccine EUA on 20 October 2021 to allow a single booster dose to be given at least 6 months following the primary doses. This vaccine is 81.6% and 95.7% effective against B.1.1.7 and B.1.351 variants, respectively. It is manufactured by ModernaTX,...
a small part of patients had a history of infection before vaccination (3/59, 5.1%) and only 10 (16.9%) patients received the third dose of the vaccination, we can conclude that infection after vaccination has a similar effect in the group as administration of the so-called booster dose....
New SARS-CoV-2 variants with varying vaccine response rates have led to different vaccination approaches across the globe with booster vaccinations and different timings being a topic of controversy and ongoing discussion. Cardiovascular complications following SARS-CoV-2 vaccination have been reported ...
Lower antibody levels elicited by different COVID-19 vaccines are associated with breakthrough infections after vaccination, prompting consideration of booster doses or choosing a different type of vaccine [49]. Wild-type infection may enhance protection from vaccination—especially at the levels of ...
booster immunization with the mRNA vaccine showed that vaccination induced a rapid antigen-specific CD4+ T cell response in naïve subjects after the first dose. At the same time, the CD8+ T cell response develops gradually. Vaccine-induced responses of Th1 and Tfh cells after the first dose...
In addition, 2.1% of the participants received more than two doses (booster doses). Two hundred and fourteen participants (35.1%) reported having a previous COVID-19 infection before vaccination, compared to only 77 (12.6%) who reported having COVID-19 infection after vaccination. Of those ...
A booster dose can also be given 6 months after the second dose [50]. Moderna vaccine should be stored in cold conditions at −25 to −15 °C. After thawing, the vaccine should be kept at 2 to 8 °C for 30 min to 2 h [51,52]. Vaccine efficacy in the age range of 18–...
The COVID-19 pandemic has seen a considerable expansion in the way work settings are structured, with a continuum emerging between working fully in-person and from home. The pandemic has also exacerbated many risk factors for poor mental health in the wo
The vaccines against COVID-19 are the best treatment for limiting the spread of the epidemic, and from an individual point of view, for avoiding getting sick. A cross-sectional retrospective survey was conducted from 15 May to 15 July 2021 among healthca
In accordance with WHO data, 66.1% of the worldwide population has been administered the last dose of the primary vaccination series, while roughly 32% have received at least one booster or supplementary dose [40]. Thus, with the increasing number of individuals receiving COVID-19 vaccinations,...