Here, we use whole genome sequencing in 7,491 critically-ill cases compared with 48,400 controls to discover and replicate 23 independent variants that significantly predispose to critical Covid-19. We identify
This work was partially presented as a poster: P0838 Whole genome sequencing characterization of Clostridioides difficile from Bulgaria during the COVID-19 pandemic with authors E. Dobreva, I. Stoikov, D. Donchev, R. Hristova, R. Vatcheva-Dobrevska, M. Murdjeva, I. Ivanov at 33rd Euro...
Initial whole-genome sequencing and analysis of the host genetic contribution to COVID-19 severity and susceptibility ArticleOpen access10 November 2020 Main The design of the GenOMICC study and the rationale for focusing on critical illness has been previously described1,2. In brief, patients with...
In partnership with Genomics England, we performed whole-genome sequencing (WGS) to improve the resolution and deepen the fine-mapping of significant signals and thereby provide further biological insight into critical COVID-19. Here we present results from a cohort of 7,491 critically ill patients...
http://weixin.qq.com/r/pUjp8SDEVH0rrWSS9x23 (二维码自动识别) 参考资料 王立铭《病毒科学 9 讲》 Initial whole-genome sequencing and analysis of the host genetic contribution to COVID-19 severity and susceptibility. 发布于 2022-12-17 22:31・广东 ...
Long reads nanopore sequencing to recover SARS-CoV-2 whole genome v.3 Resende, P. Oswaldo Cruz Institute; Pathogen Genomics Unit and UCL Genomics, University College London This protocol builds long (~2kb) amplicon libraries of SARS-CoV-2 genomes, suitable for nanopore sequencing. ...
参考资料 王立铭《病毒科学 9 讲》 Initial whole-genome sequencing and analysis of the host genetic contribution to COVID-19 severity and susceptibility. ---/ END /---
nursing home outbreakcovid-19 epidemiologyphylogenetic treewhole genome sequencinghousehold transmissionBackgroun:d Residents in nursing homes are at risk of high morbidity and mortality due to coronavirus disease 2019 (COVID-19). We report the first nursing home...
Meanwhile, the whole genome sequencing analysis of 16 cases announced earlier confirmed that they all carried the Omicron variant of COVID-19, bringing the total number of Omicron infections to 533 in Hong Kong.■ A resident registers personal information in Kwai Chung of Hong Kong, south China...
PNG has been sending its samples to Australia and Singapore for WGS results. PCR testing is the first step of Whole Genome Sequencing (WGS), the process by which new Variants of Concern (VoC) are uncovered. "Clinical laboratories are of paramount importance in mitigating the COVID-19 pandemic...