VITAMIN DVITAMIN CCOVID-19IMMUNE responseCHRONIC diseasesSevere acute respiratory syndrome coronavirus 2 (SARS-COV2) infection causes life-threatening respiratory illness, which has caused significant mortality and morbidity around the globe. Coronavirus disease 2019 (COVID-19) cause...
有研究表明维生素D缺乏与重症COVID-19风险存在关联,但受到了肥胖等常见危险因素的干扰。尚无证据明确显示补充维生素D可降低COVID-19的风险或严重程度[2]。 补充维生素D可用于满足每日推荐摄入量(15-25μg,即600-1000IU)或治疗维生素D缺乏,但不建议超量使用。 详见专题''Vitamin D and extraskeletal health', sect...
10. Janssens W, Lehouck A, Carremans C, Bouillon R, Mathieu C, Decramer M. Vitamin D beyond bones in chronic obstructive pulmonary disease: time to act. Am J Respir Crit Care Med 2009;179:630–6.
结论:维生素D在肾外代谢在防治SARS-CoV-2感染中具有潜在作用,补充维生素D可能对新冠肺炎也有潜在的防治作用。综述显示维生素D的免疫调节功能:①先天免疫反应:维生素D抑制树突状细胞的成熟,并阻止其抗原呈递到T辅助细胞。维生素D诱导巨噬...
近日,《PLOS ONE》期刊将上月刚发表的一篇论文标记为“Expression of Concern(EoC)”,该研究表明维生素D或可以预防COVID-19进展为重症。期刊所发出的通知中,指出的文章存在的核心问题是,作者似乎夸大了维生素D和COVID-19之间的相关性。 这篇文章的题目为“Vitamin D sufficiency, a serum 25-hydroxyvitamin D at ...
Mechanistic and observational evidence suggests that COVID-19 is less severe in people with adequate vitamin D levels. Vitamin D supplementation seems to help prevent COVID-19 complications, but only two randomized trials have been conducted thus far...
4.Laird E Rhodes J Kenny RA Vitamin D and inflammation: potential implications for severity of COVID-19. Ir Med J. 2020; 113: 81 5.Ilie PC Stefanescu S Smith L The role of vitamin D in the prevention of coronavirus disease 2019 infection and mortality. Aging Clin Exp Res. 2020; ...
4.Laird E Rhodes J Kenny RA Vitamin D and inflammation: potential implications for severity of COVID-19. Ir Med J. 2020; 113: 81 5.Ilie PC Stefanescu S Smith L The role of vitamin D in the prevention of coronavirus disease 2019 infection and mortality. Aging Clin Exp Res. 2020; 32...
12.Tan CW, Ho LP, Kalimuddin S, Cherng BPZ, Teh YE, Thien SY, et al. Cohort study to evaluate the effect of vitamin D, magnesium, and vitamin B(12) in combination on progression to severe outcomes in older patients with coronavirus (COVID-19...
4.Laird E Rhodes J Kenny RA Vitamin D and inflammation: potential implications for severity of COVID-19. Ir Med J. 2020; 113: 81 5.Ilie PC Stefanescu S Smith L The role of vitamin D in the prevention of coronavirus disease 2019 infection and mortality. Aging Clin Exp Res. 2020; 32...