Risk factors associated with an increase in PROs after COVID-19 vaccination were analyzed using logistic regression analyses. In addition, we assessed whether there were differences in variables by vaccine order using the linear mixed model. Results: In multivariate analysis, young...
ChAdOx1 nCoV-19 (also known as AZD1222), developed byAstraZeneca, is a replication-deficient chimpanzee recombinant adenoviral vector vaccine containing the SARS-CoV-2 spike protein administered as a two-dose prime-boost regimen. The interim analysis of randomized controlled trials of ChAdOx1 nCoV-...
Varied technology, varied pros and cons Some vaccine technologies are well established [e.g. inactivated or live-attenuated whole virus, or viral subunit (protein or virus-like particles)], but COVID-19 vaccines have employed technologies such as novel modified viral mRNA or DNA approaches [4]...
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COVID-19 and its consequences present an ongoing constraint to the management of NTDs The lack of vaccine equity is ongoing despite the best efforts of WHO and partners. In 2022, 116 countries were still short of the target of 70% of the population vaccinated against COVID-19 [89] despite...
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the most formidable challenge to humanity in a century. It is widely believed that prepandemic normalcy will never return until a safe and effective vaccine strategy becomes...
Women were slightly more likely than men to say they were very or somewhat likely to get the new vaccine, but the National Poll on Healthy Aging revealed starker contrasts between other demographic groups. Respondents with at least a bachelor’s degree, for example, were more liable to report...
This cluster randomized clinical trial aims to determine whether provision of COVID-19 vaccine messaging platforms in emergency departments increases
5Current advances in vaccine development Besides the aim of developing effective drugs to treat COVID-19, efforts have also been made to develop promising vaccines that can boost immunity and control the viral infection. Globally, 13.6 billion doses have been administered, 67% of the total popula...
vaccine candidates. It is worth noting that it is currently difficult to compare the various vaccines as there are no standardized assays for neutralization and challenge studies. The pros and cons of these vaccine candidates with the respective targets and strategies will need to be further ...