The objective is to simultaneously minimize 1) the fixed cost for operating vaccination sites; 2) the traveling distance of vaccine recipients; 3) the appointment rejection cost; and 4) the vaccination tardiness cost. We formulate the problem as a mixed-integer linear program (MILP). Given the...
According to statistics, China has provided a total of nearly two billion doses of COVID -19 vaccines to the world, mostly to developing countries, accounting for one-third of the global vaccine use outside of China, and in process becoming the biggest foreign provider of COVID...
decision-making when counseling pregnant and nursing women about the unstudied benefits and risks COVID-19 vaccination, calling for rigorously designed studies with real-time, proactive data collection to establish evidence as quickly as possible about coronavirus vaccine safety in mothers and their ...
There is need for effective and affordable vaccines against SARS-CoV-2 to tackle the ongoing pandemic. In this study, we describe a protein nanoparticle vaccine against SARS-CoV-2. The vaccine is based on the display of coronavirus spike glycoprotein rec
疫苗前景可期,但仍有失败的可能,万一安全而有效的COVID-19疫苗未能研制成功或者需要更多的时间,中国将与国际科学界合作,确定有效药物和治疗策略;通过通信技术创新,支持病例管理和识别有被感染风险的密切接触者;评估众多COVID-19防控措施的有效性和影响;公众参与评估社会对特定控制措施的接受程度。这些均将有助于政策制...
In conclusion, the present study demonstrated that recovered COVID-19 patients receiving either one dose or multiple doses of the vaccine all have significantly larger booster effects on the potency and breadth of NAbs and the magnitude of humoral and cellular immune responses, which would maintain...
其他相对不常见的COVID-19并发症也可导致精神状态改变,包括缺血性或出血性脑卒中、脑炎、可逆性后部脑病综合征(posterior reversible encephalopathy syndrome, PRES)、多系统炎症综合征以及感染后脱髓鞘疾病。 表1 (3)评估与处理 如果患...
原文出处:Sanofi-GSK first to report a successful efficacy study against Omicron with COVID-19 Beta-containing vaccine 识别微信二维码,添加生物制品圈小编,符合条件者即可加入微信群! 本公众号所有转载文章系出于传递更多信息之目的,...
COVID19 dataset list 🦠 To accelerate the COVID-19 research and vaccine development we collected a list of publicly available datasets with single-cell (scRNAseq) and immune repertoire (AIRR / RepSeq / immunosequencing) data. The data comes from confirmed COVID-19 patients or from human ce...
Most COVID-19 vaccines are designed to elicit immune responses, ideally neutralizing antibodies (NAbs), against the SARS-CoV-2 spike protein. Several vaccines, including mRNA, adenoviral-vectored, protein subunit and whole-cell inactivated virus vaccines