Host-pathogen interaction in COVID-19: Pathogenesis, potential therapeutics and vaccination strategies - ScienceDirectCOVID-19SARS-CoV-2Life-cyclePathophysiologyCo-morbiditiesPregnancyVaccineAnti-viralsThe current coronavirus pandemic, COVID-19, is the third outbreak of disease caused by the coronavirus ...
The laboratory parameters-derived CoLab score as an indicator of the host response in ICU COVID-19 patients decreases over time: a prospective cohort study Tom Schoenmakers Mathie P. G. Leers the CoLaIC-consortium ArticleOpen Access8 Apr 2024 Scientific Reports Comprehensive antibody and cytokin...
In this review, we describe the current knowledge on COVID-19 and the significance of wildlife hosts in its emergence. Mammalian and avian coronaviruses have diverse host ranges with distinct lineages of coronaviruses. Recombination and reassortments occur more frequently in mixed-animal markets ...
There have been hundreds of millions of cases of coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). With the growing population of recovered patients, it is crucial to understand the long-term consequences of the disease and ...
It depicts the roles of molecular and cellular entities in virus-host interactions and in the virus life cycle, as well as a wide spectrum of medical and epidemiological concepts linked to COVID-19. The performance of the ontology has been tested on Medline and the COVID-19 corpus provided ...
1:16 min Is it helpful to take vaccination records with you when leaving Ukraine to reside in a host country? 0:16 min Can a person receive routine vaccination for adults (e.g., Tdap vaccine against tetanus/diphtheria/pertussis) and COVID-19 vaccination during the same visit? 1:24 min ...
• Weather and climate serve as environmental drivers in propagating COVID-19. • Solar radiation influences the spreading of COVID-19. • The correlation between weather and population as the factor in spreading of COVID-19. Graphical abstractIntroduction...
In addition, LH is efficacious in the animal models of MERS. Fig. 2 The replication cycle of SARS-CoV-2 and the targets of various therapeutic drugs. SARS-CoV-2 recognizes the ACE2 receptor on the host cell membrane via the RBD of spike protein, and enters host cell. Once uncoating, ...
1.4. Coronavirus life cycle 1.4.1. Steps 1.5. Epidemiology In December 2019, several cases of pneumonia were reported, grouped together in Wuhan City, and the source was based on the Huanan Seafood Market. The first case of COVID-19 was discovered with unexplained pneumonia on December 12, ...
The genome structure, the encoded structural and nonstructural proteins, and the key host of SARS-CoV-2 are illustrated in Fig. 3.1. Experimental evidences have clearly shown that SARS-CoV-2 infects humans by binding to angiotensin-converting enzyme 2 (ACE2) expressed in the respiratory tract,...