COV2: Ed. Board Author links open overlay panel https://doi.org/10.1016/S1077-3142(11)00052-X Previousarticlein issue Nextarticlein issue View PDF Cited by (0) View Abstract Special issue on 3D Imaging and Modelling Edited by AdrianHilton,GuyGodin,ChangShu,TakeshiMasuda...
1. SARS-Cov2 characteristics and infection 2. Innate immune response against SARS-Cov2 3. Acquired immune response 4. Tolerance breakdown 5. SARS-COV-2/Covid19 vaccination and autoimmune and chronic inflammatory diseases: friends, foes or both 6. Conclusion Funding Declaration of competing interest...
The spike (S) protein of SARS-CoV-2 is significant since it mediates receptor binding and cell entry and is the , dominant target of the immune system.It exhibits substantial conformational flexibility, transitioning from a closed to open conformations to expose its receptor-binding site. The RBD...
DockCoV2 The current state of the COVID-19 pandemic is a global health crisis. To fight the novel coronavirus, one of the best-known ways is to block enzymes essential for virus replication. Currently, we know that the SARS-CoV-2 virus encodes about 29 proteins such as spike protein, 3C...
Introduction SARS-CoV-2 has been identified as the cause of the disease officially named COVID-19, primarily a respiratory illness. COVID-19 was characterised as a pandemic on 11 March 2020. It has been estimated that approximately 20% of people with COVID-19 require oxygen therapy. Oxygen ...
A SARS-CoV2 super-spreading event occurred during carnival in a small town in Germany. Due to the rapidly imposed lockdown and its relatively closed community, this town was seen as an ideal model to investigate the infection fatality rate (IFR). Here, a 7-day seroepidemiological observational...
At the time of writing, there are already millions of documented infections worldwide by the novel coronavirus 2019 (2019-nCoV or severe acute respiratory syndrome coronavirus 2 (SARS-CoV2)), with hundreds of thousands of deaths. The great majority of fatal events have been recorded in adults ...
On The Origin of SARS-COV2 Virusdoi:10.2139/ssrn.3631469SARS-COV2COVID-19mutation rateoriginevolutionSARS-COV2 is originated from a closely related bat Coronavirus RaTG13 after gaining insertions by exchanged recombination with pangolin virus Pan_SL_COV_GD. SARSocial Science Electronic Publishing...
Antiviral strategies to inhibit Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) and the pathogenic consequences of COVID-19 are urgently required. Here, we demonstrate that the NRF2 antioxidant gene expression pathway is suppressed in biopsie
Nature. (2020), 10.1038/s41586-020-2196-x Advance online publication Google Scholar 29 M. Shinjoh, K. Omoe, N. Saito, N. Matsuo, K. Nerome In vitro growth profiles of respiratory syncytial virus in the presence of influenza virus Acta Virol., 44 (2000), pp. 91-97 View in Scopus...