图1 covSPECTRUM网站分析最新变异株的相对增长速率流程图 2. 获得变异株的GISAID序列号 看到FY.3获得了全球变异株相对增长速率Top1的宝座,如果你兴致勃勃地去GISAID官网通过谱系号栏搜索“FY.3”大概率只能得到“No data found”的结果。那如何获得序列呢?其实covSPECTRUM网站已经给列出来了:点击FY.3后,在新的网页...
The reduced NAb epitope diversity caused by imprinted humoral response could be shown by the estimated mutation preference spectrum (Fig.4a). Diversified escaping-score peaks, which also represent immune pressure, could be observed when using BA.2-elicited antibodies, whereas only two major peaks cou...
Before the emergence of BA.4 and BA.5, F486V in the receptor-binding domain (RBD) of spike had been observed in only 54 of 10 million publicly available genome sequences in GISAID (https://cov-spectrum.org/explore/World/AllSamples/AllTimes/variants?aaMutations=S%3AF486V&). Selection ...
[16] Yuan, Shuofeng et al. “Targeting papain-like protease for broad-spectrum coronavirus inhibition.” Protein & cell, 1–14. 6 Apr. 2022, doi:10.1007/s13238-022-00909-3 [17] Zhang, Linlin et al. “Crystal stru...
该研究题为“An enhanced broad-spectrum peptide inhibits Omicron variants in vivo”,发表在Cell Reports Medicine杂志。 来源:https://doi.org/10.1016/j.xcrm.2024.101418 为了开发强效、广谱的抗冠状病毒抑制剂,研究人员首先通过相对较...
more sensitive for partial sequences (it catches all the 3 that are already on covSpectrum, 7 of the 10 sequences were uploaded to GISAID just today so it will take up to 3 more days for them to show up on covSpectrum):https://cov-spectrum.org/explore/World/AllSamples/Past6M/...
The SPIRIT-Outcomes 2022 Extension Mass Violence and the Complex Spectrum of Mental Illness and Mental Functioning Neuropsychiatry Sequelae of COVID-19 A New Framework for Dementia Nomenclature Organization and Performance of US Health Systems Pharmacy Benefit Managers: History, Business Practices, Economics...
[16] Yuan, Shuofeng et al. “Targeting papain-like protease for broad-spectrum coronavirus inhibition.” Protein & cell, 1–14. 6 Apr. 2022, doi:10.1007/s13238-022-00909-3 [17] Zhang, Linlin et al. “Crystal structure of SARS-CoV-2 main protease provides a basis for design of improv...
Furuta Y, Komeno T, Nakamura T (2017) Favipiravir (T-705), a broad spectrum inhibitor of viral RNA polymerase. Proc Jpn Acad Ser B Phys Biol Sci 93:449–463 Article CAS PubMed PubMed Central Google Scholar Gallart JM, Galard R, Catalan R, Arguello JM, Castellanos JM, Schwartz S (...
The SPIRIT-Outcomes 2022 Extension Mass Violence and the Complex Spectrum of Mental Illness and Mental Functioning Neuropsychiatry Sequelae of COVID-19 A New Framework for Dementia Nomenclature Organization and Performance of US Health Systems Pharmacy Benefit Managers: History, Business Practices, Economics...