Data dependent MS2 spec- tra of precursor ions were acquired with a resolution of 17,500 FWHM, an AGC target of 5 × 105, 100 ms MIT and a normalized collision energy of 30. An exemplary extracted ion chromatogram (XIC) and an ESI–MS/MS spectrum can be found in the ...
of the main regulatory epigenetic mechanisms51. This modification, in most cases, impairs transcription factor binding in the CpG-rich promoter region of a gene52, thereby leading to lower transcription. However, it still remains elusive why susceptibility to environmental cues is especially high duri...
of the main regulatory epigenetic mechanisms51. This modification, in most cases, impairs transcription factor binding in the CpG-rich promoter region of a gene52, thereby leading to lower transcription. However, it still remains elusive why susceptibility to environmental cues is especially high duri...