The reactivity of this dielectrophile was tested by reaction with aniline and phenol, a nitrogen and oxygen nucleophile, respectively. The new dielectrophile would further provide an ideal platform for the construction of large hetero-atom bridged macrocycles for desired properties and functions in ...
Electrochemical process for coupling of phenol to anilineEvonik Degussa Gmbh
Ze-Kun Yang1, Kazunori Miyamoto1, Shinsuke Komagawa4, Kentaro Yamaguchi3, Chao Wang1,2 & Masanobu Uchiyama1,2 Cross-coupling is a fundamental reaction in the synthesis of functional molecules, and has been widely applied, for example, to phenols, anilines, alcohols, amines and their derivativ...
Pd(II)-β-cyclodextrin complex: Synthesis, characterization and efficient nanocatalyst for the selective Suzuki-Miyaura coupling reaction in water •Preparation of novel water soluble Pd(II)-β-cyclodextrin complex without any ligand.•Suzuki-Miyaura catalytic coupling reaction with high TOF (105m.....
Barton's approach was successfully used to synthesize anilines through basic amine and indole arylation; however, the approach exhibited difficulties in proceeding with the less reactive NH compounds. Moreover, reaction conditions were quite adverse as a consequence of strong bases and high temperatures...
Cross-coupling is a fundamental reaction in the synthesis of functional molecules, and has been widely applied, for example, to phenols, anilines, alcohols, amines and their derivatives. Here we report the Ni-catalysed Stille cross-coupling reaction of quaternary ammonium salts via C–N bond clea...
SnCl2 catalyzed the three-component coupling of aniline, epoxide, and paraformaldehyde, resulting in the synthesis of 1,3-oxazolidine derivatives. The reaction is simple and does not require any additives, bases, or oxidants, and proceeds at moderate temperature with good functional group tolerance. ...
diazo-coupling reaction重氮-偶合反应 1.A nonlinear chromophore containing azo group,1-n-butoxy-2,5-dimethyl-4-(4′-nitrophenyl-azo)benzene,was synthesized with 4-nitroaniline,sodium nitrite,2,5-dimethylphenol and n-butyl bromide via diazo-coupling reaction.以对硝基苯胺、亚硝酸钠、2,5-二甲基苯酚...
The diazonium salt is typically generated in situ by the reaction of a primary aromatic amine with sodium nitrite in acidic conditions. The azo component is usually an activated aromatic compound, such as aniline or phenol. The reaction proceeds through a series of nucleophilic aromatic substitution...
Transition metal-catalysed C–H functionalization and decarboxylative coupling are two of the most notable synthetic strategies developed in the past 30 years. Here, we connect these two reaction pathways using bases and a simple Pd-based catalyst system to promote a para-selective C–H functionaliza...