The Chicken Ovalbumin Upstream Promoter Transcription Factor II (COUP-TFII, NR2F2) is a NR classified as an orphan due to the lack of a known natural ligand. Although its expression peaks during development, and then decreases considerably, in adult tissues, COUP-TFII is an important regulator...
ca1是海马内部的主要输出区域,纤维延伸到海马下托、伞部,然后是穹窿;且存在ca1与海马下托之间的辅助联系。 11、 coup-tfii基因发现于1986年,全称为chicken ovalbumin upstream promotertranscriptional factor ii (鸡卵清蛋白上游启动转录因子ii),又名 nr2f2、 arp-1,属于类固醇激素核受体超家族成员。在哺乳动物中...
COUP-TFII / NR2F2 Antibody (N-Terminus) LS-C356225 中文名: 中文别名: CBNumber: CB86514118 分子式: 分子量: 0 MOL File: Mol file 化学性质安全信息用途供应商1 COUP-TFII / NR2F2 Antibody (N-Terminus) LS-C356225化学性质 安全信息
COUP-TFII(NR2F2) has key roles in neuronal and eye development, tumorigenesis, and metastasis[42,43]. It has only one crystal structure elucidated[44]. This structure exhibited an autorepressed H12 conformation and featured only 11 α-helices. Although COUP-TFII crystallizes as a monomer, it ...
COUP-TFII (aka NR2F2) is a nuclear receptor that has been shown to play an important role in mesoderm formation, including the development of blood vessels (Davis et al., 2013; Wu et al., 2016). Mesenchymal stem cells are multipotent cells with the capacity to give rise to multiple ...
(redirected fromCOUP-TFII) NR2F2 A gene on chromosome 15q26 that encodes a member of the steroid thyroid hormone superfamily of nuclear receptors, which is a ligand-activated transcription factor involved in regulating a wide range of genes. ...
COUP-TFII (COUP transcription factor 2), also known as NR2F2 (nuclear receptor subfamily 2, group F, member 2) is a protein that in humans is encoded by the NR2F2 gene. The COUP acronym stands for chicken ovalbumin upstream promoter.COUP-TFII plays a critical role in controlling the ...
The chicken ovalbumin upstream promoter transcription factors (COUP-TFs), members of the nuclear receptor superfamily, consist of two highly homologous subtypes, COUP-TFI (EAR-3, NR2F1) and COUP-TFII (ARP-1, NR2F2). They are referred to as orphan receptors because the COUP-TF ligands have...
NR2F2 、 ARP-1 ,属于类固醇激素核受体超家族成员。在哺乳动物中除了COUP-TFII之外,还有COUP-TFI。因为COUP-TFs天然的配体还未被发现,所以COUP-TFs又被称为孤儿受体。其结构包括活化功能区1,参与到辅助激活物的招募、DNA结构域、核定位序列、活化功能区2及配体结合结构域和C末端区域。COUP-TFII和-TFI在蛋白结构...
A regulatory circuitry comprised of miR-302 and the transcription factors OCT4 and NR2F2 regulates human embryonic stem cell differentiation Here, we show that the transcriptional factors OCT4 and NR2F2 (COUP-TFII) and the miRNA miR-302 are linked in a regulatory circuitry that critically ......