The antimicrobial drug Co-trimoxazole presents a wider spectrum of activity as compared with the action of each one of its two components when utilized individually.Co-trimoxazole is active upon the majority of pathogenic bacteria among which are those that today constitute great probleme, specially ...
Antimicrobial Action The actions and spectrum of activity of co-trimoxazole are essentially those of its components, sulfamethoxa- zole (p.341) and trimethoprim (p.356). Because they act at different points of the folate meta- bolic pathway a potent synergy exists between its com- ponents in...
Synopsis: Co-trimoxazole1 (trimethoprim-sulfamethoxazole) is a 'broad spectrum' antimicrobial which is active in vitro against a wide variety of micro-organisms. Clinical experience with this agent now spans a decade or more in many countries. While it is clearly established as the agent of first...
CefiximeThe cephalosporins are broad-spectrum antibiotics. The four generations of agents display increasing activity against gram-negative aerobes, and somewhat decreasing activity against gram-positive organisms. These antibiotics, which block transpeptidase activity of penicillin-binding proteins, are employed...
Synopsis Ciprofloxacin belongs to the fluoroquinolone class of antimicrobial agents which primarily inhibit bacterial DNA gyrase. It is effective after oral or intravenous administration, demonstrating potent antibacterial activity aga... LR Wiseman,JA Balfour - 《Drugs & Aging》 被引量: 19发表: 2012年...
Co-trimoxazole is an inexpensive, broad-spectrum antimicrobial drug that is widely used in developing countries. Before antiretroviral therapy (ART) scale-up, co-trimoxazole prophylaxis reduced morbidity and mortality in adults and children with HIV by preventing bacterial infections, diarrhoea, malaria,...