The meaning of COTRANSPORTER is a specialized protein of cell membranes that mediates cotransport. How to use cotransporter in a sentence.
Meaning In patients with type 2 diabetes, the use of SGLT-2 inhibitors or GLP-1 agonists was associated with better mortality outcomes than DPP-4 inhibitors. Abstract Importance The comparative clinical efficacy of sodium-glucose cotransporter 2 (SGLT-2) inhibitors, glucagon-like peptide 1 (GLP-...
Meaning In this study, use of SGLT2i for HFrEF in the US was overall low and highly variable across hospitals. Abstract Importance Clinical guidelines for patients with heart failure with reduced ejection fraction (HFrEF) strongly recommend treatment with a sodium-glucose cotransporter-2 inhibitor (...
Many of the historical and recent data that have emerged from the experiments conducted will be outlined and their larger meaning will also be placed into perspective with the aid of various hypotheses. Na+–K+–Cl cotransporter 2 (NKCC2) mediates the cotranslocation of Na+, K+, and Cl ...
Only adult 90-d-old rats revealed a well-established circadian rhythm expression for the cotransporter SGLT-1 protein. Similar results are already reported by other studies (Stearns et al.–2009; Balakrishnan et al.). The physiological meaning of this daily profile for the molecular expression of...
CKD-PCP has dual meaning: it applies to providers who most often care for patients with T2DM ( C ardiologists, K idney specialists, D iabetologists, and P rimary C are P hysicians) and it refers to the benefits of SGLT2i (treatment of C ardiovascular disease, K idney disease, ...
Meaning This study’s findings found a rapid clinical benefit of SGLT2 inhibitors, suggesting that their use may be beneficial for most individuals with heart failure. Abstract Importance Emerging evidence has consistently demonstrated that sodium-glucose cotransporter 2 (SGLT2) inhibitors reduce the ris...
Ascertainment of the “incident” events is limited by the clinical presentations of OAD, meaning that SGLT2Is may reduce OAD symptoms rather than prevent a patient from developing the disease. Conclusions In this retrospective cohort study of patients with type 2 diabetes in Hong Kong, SGLT2I ...
Meaning These findings suggest that SGLT2-Is may be associated with an overall cardiovascular benefit for patients with high-risk cardiovascular features compared with placebo in both sexes, different age groups and different races and ethnicities. Abstract Importance The cardiovascular outcome in selected...
MeaningThe gout and cardiovascular benefits associated with SGLT2i in these target trial emulations may guide selection of glucose-lowering therapy in T2D patients, at risk for or with gout. Abstract ImportanceSodium-glucose cotransporter type 2 inhibitors (SGLT2i) are a revolutionar...