Cost estimates in the front-end phase of public projects are critical in ensuring the selection of good projects that provide value for society. In this study, we use theoretical perspectives of front-end and cost estimation under uncertainty to address the gap in project management research on ...
This review examines the various modelling approaches taken to evaluate the cost effectiveness of vaccination programmes. First we provide an overview of key attributes of general models used to conduct cost-effectiveness analyses (CEAs). We then describe the basic characteristics of the CEAs of curr...
3.1.2. The appraisal of medical devices There has been much greater activity in the assessment of novel pharmaceuticals than of medical devices in the UK. There are a number of reasons for this. First, the expenditure of devices may not be so visible [76], in so far as some devices rep...
Spinal muscular atrophy is a rare neuromuscular disorder with a spectrum of severity related to age at onset and the number of SMN2 gene copies. Infantile-
2. Creation of database and optimised case report form for prospective identification of DILI cases and well-characterised controls, biological samples, and imaging data 3. Preclinical models in DILI to improve the assessment and prediction of hepatotoxicity to guide future drug safety testing 4. Cli...
Use of quality adjusted life years and life years gained as benchmarks in economic evaluations: a critical appraisal. Health Care Manage Sci 2004; 7: 43–9 CrossRef Stinnett AA, Mullahy J. Net health benefits: a new framework for the analysis of uncertainty in cost-effectiveness analysis. ...
Nevertheless, Pearce (1971) states that the first practical use was in the USA as a part of a national appraisal mechanism for dam construction in 1936; within the Flood Control Act, the most systematic use of this method occurred in 1960s (Nas 2016). Sweden also started using CBA in ...