Associations and their maintenance may present another, more subtle, context of sexual conflict in addition to forced copulations in orangutans. Following the “cost-of-sexual-attraction” hypothesis (Wrangham2002), high costs of association may be responsible for the absence of morphological fertility ...
Improving physical activity and reducing sedentary behavior represent important areas for intervention in childhood in order to reduce the burden of chronic disease related to obesity and physical inactivity in later life. This paper aims to determine the cost-effectiveness of a multi-arm primary school...
A non-randomized controlled trial, conducted from June 2018 to March 2019 in two rural communes in the health district of Mayahi in Niger, showed that including community health workers (CHWs) in the treatment of severe acute malnutrition (SAM) resulted in a better recovery rate (77.2% vs. ...
which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third...
Additionally, we used the HR for the sustained eGFR decrease < 15 mL/min/1.73 m2 to adjust for the effect of finerenone on progression to CKD 5. As the median follow-up duration in the FIDELIO-DKD trial was 2.6 years, HRs to account for the longer-term risk of a CV event (...
Nucleic acid test (NAT) could effectively control the spread of COVID-19 caused by large-scale sports competitions. However, quantitative analysis on the appropriate frequency of NAT is scarce, and the cost-effectiveness and necessity of high-frequency N
Don't be out of pocket on Jury Service How long to keep important documents and where Everything you need to know about the Budget Stay savvy on Black Friday How to find your lost pension money All you need to know about income protection ...
Since the PFS curves of tislelizumab before and after MAIC adjustment relative to the chemotherapy group and the PFS curves of camrelizumab relative to the chemotherapy group did not meet the PH assumption (Supplementary Figures S1-S2), the MAIC-adjusted HR values were not used to adjust...
Hazard ratios (HR) of mortality rates in SVR vs. no SVR were applied to determine the SVR state mortality rates [21]. For patients with F0-F1 (no fibrosis and mild fibrosis) and patients without HCV infection, we assumed the same utility. Liver-related healthcare costs were derived from ...
To assess the cost-effectiveness of using cheaper-but-noisier outcome measures, such as a short questionnaire, for large simple clinical trials. To detect associations reliably, trials must avoid bias and random error. To reduce random error, we can incr