Value in HealthCost-effectiveness analysis of micafungin versus caspofungin for treatment of systemic Candida infections in the UK[J] . M. K. Sidhu,A. K. van Engen,J. Kleintjens,O. Schoeman,M. Palazzo.Current Medical Research and Opinion . 2009 (8)...
*I am grateful to Helen Hughes of the Australian National University for stimulating the work on which this paper is based, and to Russel Cooper and two anonymous referees for comments on an earlier draft. The research assistance of Gary Madden and Margaret Smith is acknowledged. † *I am ...
All costs, years of life lived and quality adjusted life years (QALYs) lived were discounted at an annual rate of 5%. Over a 20-year model period, first-line use of combination dapagliflozin and metformin was predicted to reduce the onset of hospitalisation of heart failure, cardiovascular ...
From 3 µg to 5 µg of unfractionated tryptic digests that are obtained from proteomics-typical amounts of starting material, microLC-SWATH-MS quantifies up to 4000 human or 1750 yeast proteins in an hour or less. In the acquisition of 750 yeast proteomes, retention times varied ...
Although their efficacy for preventing cervical cancer has not been comprehensively proven yet, it seems reasonable to expect such an outcome. A number of studies have been conducted to evaluate the potential cost-effectiveness for prevention of cervical cancer through HPV vaccination, with a range ...
The link between EDR and cost of capital also relates to the notion of information acquisition. When high expectations exist about a value-relevant signal, such as an earnings downward pattern, investors are likely to engage in information acquisition to better understand it. This results in high...
Spinal muscular atrophy is a rare neuromuscular disorder with a spectrum of severity related to age at onset and the number of SMN2 gene copies. Infantile-
Somatic copy number alterations (SCNAs) are an important class of genomic alteration in cancer. They are frequently observed in cancer samples, with studies showing that, on average, SCNAs affect 34% of a cancer cell’s genome. Furthermore, SCNAs have been shown to be major drivers of tumo...
An entirely different approach to handling dimensionality issues has been offered by the recently proposed performance-driven modeling frameworks47,48,49. The key concept of the methods belonging to this class is to restrict the metamodel domain to the most promising region of the parameter space, ...
Achieving broadband absorption has been a topic of intensive research over the last decade. However, the costly and time consuming stage of lithography has always been a barrier for the large-area and mass production of absorbers. In this work, we design