Multiple hypothesis testing is a major issue in genome-wide association studies (GWAS), which often analyze millions of markers. The permutation test is considered to be the gold standard in multiple testing correction as it accurately takes into account
The image data is lit using the surface normal of each voxel. This normal is approximated directly in the shader by finding the gradient direction for each pixel based on a 3×3×3 neighborhood. Lighting of this kind gives a more three dimensional feel to the image even when viewed on a...
is the most commonly used scale for determining the severity of chest wall deformities. The index is defined as the width of the chest divided by the distance between the sternum and spine at the point of maximal depression. The normal value is 2.54. In individuals with pectus carinatum, a...
In the present study we demonstrate that when young, both male and female Sorcs1 -/-, APP/PSEN1 and Sorcs1 -/- x APP/PSEN1 mice display normal glucose homeostasis. This fits with previous studies that have shown that young APP/PSEN1 mice have similar glucose tolerance to WT mice when fed...
regulated Epo expression system 679 we constructed can drive the Epo gene and protein expression in response to hypoxia, and those in vivo confirm that this system can correct the uremic anemia and, more importantly, can maintain the Hct within the normal range for long time in the uremic ...
Schlamowitz, I. An analysis of the time relationships within the cardiac cycle in electrocardiograms of normal men. I. The duration of the Q-T interval and its relationship to the cycle length (R-R interval).Am. Heart. J.31, 329–342 (1946). ...
The patients who fail to wake in the morning are those in whom normal sleep has masked the premonitory signs and this has no influence on their employability, even if it may occasionally affect their punctuality. 展开 DOI: 10.1136/oem.16.2.175 年份: 1959 ...
GDP is released by the National Bureau of Statistics as quarterly data, while the variables used to predict GDP are mainly monthly data, such as consumption, investment, trade, inflation rate and money supply. Due to the difference in data frequency, mixed-frequency data must be processed ...
Therefore, the skew-normal distribution is exploited as a weight for the weighted median filter. The proposed filter combines the original weighted median filter and modifies the weight kernel to suppress the noise while preserving the meaningful structure. In the following, we explain the proposed ...
2008, 2009). Responses to unilateral prosthetic stimulation exhibited excitation–inhibition asymmetry both before and after precompensation, similar to responses of animals with a single normal labyrinth experiencing natural head rotation stimuli. Asymmetry of responses to unilateral prosthetic stimulation ...