Whole genome sequences (WGS) enable discovery of rare variants which may contribute to missing heritability of coronary artery disease (CAD). To measure their contribution, we apply the GREML-LDMS-I approach to WGS of 4949 cases and 17,494 controls of European ancestry from the NHLBI TOPMed pr...
The FDA-approved product labeling for the Beta-Cath System states that it should not be used for patients with unprotected left main coronary artery disease (50 % narrowing of the coronary artery) or for patients who are not candidates for blood-thinning drugs or anti-platelet therapy. A rando...
Coronary artery diseaseBackground:Chronic total occlusion (CTO) of the coronary artery is a complex condition necessitating special care, and the prognosis may vary due to differences in technical and human resources between urban and rural hospitals.#Aim:To evaluate differences in mortality and ...
Rule out obstructive coronary stenosis in persons with a low or intermediate pre-test probability of coronary artery disease or atherosclerotic cardiovascular disease by Framingham risk scoring, Pooled Cohort Equations, or by American College of Cardiology (ACC) criteria (see Appendix) with a positive ...
In this study, female beneficiaries were more likely to have an unplanned (vs elective) admission and had a higher comorbidity burden than male beneficiaries, supporting prior findings35,36 that female beneficiaries with coronary artery disease are referred later for surgery. This later dis...
Coronary artery disease (CAD) has been the leading cause of death worldwide for many years1. In Korea, CAD ranks second for mortality of all single-organ diseases2. In patients with CAD, depressive symptoms are common with a prevalence of 20%3. Depression is more prevalent during index hosp...
Arrhythmias are common after cardiac surgery such as coronary artery bypass grafting surgery. Although most of these arrhythmias are transient and have a benign course, it may represent a significant source of morbidity and mortality. Postoperative arrhy
Aims The purpose of this study was to evaluate whether there are differences in use and outcome of implantable cardioverter defibrillator (ICD) therapy with or without cardiac resynchronization therapy (CRT) between patients with underlying coronary artery disease (CAD) and non-ischemic dilated cardiomyo...
BACKGROUND Coronary artery disease (CAD) is associated with cancer. The role of inflammation in the association of CAD with cancer remains unclear. The study investigated whether inflammation could impact the relationship between CAD and lung cancer. METHODS The study involved 96 newly diagnosed lung...
The outcome in this study was incidence of ischaemic/coronary heart disease (in this study: CHD) defined according to the 9th and 10th international classification of diseases (ICD), i.e., I20–I25 (ICD-10) from 1997 or 410–414 (ICD-9) prior to 1997. Ascertainment of the potential co...