While the frequent topical corticosteroid use is associated with risk of intraocular pressure (IOP) elevation and poor patient compliance that leads to graft failure and the requirement for a repeated, high-risk corneal transplantation. Here, we developed dexamethasone sodium phosphate (DSP)鈥搇oaded ...
Postoperative complications included autograft keratomalacia, graft dehiscence and corneal pigmentation. No patient required additional surgery. Good structural and functional outcome was accomplished in 14 of 16 eyes.#Autologous corneal grafts provide tectonic support and result in good corneal transparency ...
Corneal allograft rejection remains a major cause of graft failure. High-level evidence to vindicate the use of a particular approach or treatment to prevent or treat corneal graft rejection is lacking. In the absence of extensive data from randomized, controlled clinical trials, corneal graft ...
Corneal Graft Failure . Ciba Foundation Symposium 15 (new series ) . Amsterdam: Elsevier Excerpta Medica North�Holiand 1973: 1 5 1-67. 256 Coster DJ: Factors affecting the outcome of corneal transplantatio n . Ann Royal Coli Surg Eng 1 981 , 63: 91-7. 257 Volker-Dieben H J M ...
Prevention of corneal graft failure with the immuno suppressive drug azathioprine. Lancet 1967;ii:479-82. 9. Bernauer W, Ficker LA, Watson PG, Dart JKG. The management of corneal perforations associated with rheumatoid arthritis. Ophthalmology 1995; accepted for publication. 10. Hoi M, Gna...
An Update on Novel Ocular Nanosystems with Possible Benefits in the Treatment of Corneal Neovascularization 2022, International Journal of Nanomedicine Role of immune cell diversity and heterogeneity in corneal graft survival: A systematic review and meta-analysis 2021, Journal of Clinical Medicine View ...
Nanoparticle-hydrogel composite as dual-drug delivery system for the potential application of corneal graft rejection Immune rejection remains the major cause of corneal graft failure. Immunosuppressants (such as rapamycin; RAPA) adjunctive to antibiotics (such as levoflox... X Xu,Y Wu,R Gu,......
Corneal pachymetry may be useful in assessing candidates for penetrating keratoplasty (corneal transplant), and assessing graft failure and the need for regrafting in corneal transplant recipients by aiding in the early diagnosis and treatment of graft rejection. Corneal pachymetry may also be useful ...
When this occurs, patients need to apply topical eyedrops hourly to rescue the corneal grafts from failure. The tedious process of eyedrop dosing causes a tremendous burden for patients. The resulting noncompliance to medication treatment can lead to even higher graft-rejection rates. Researc...
The use of topical steroids remains the main treatment after corneal transplant surgery to prevent and treat graft rejection, which is the principle cause of transplant failure (Price et al., 2009a). Standard corneal graft immunosuppression treatment regimen is based on topical corticosteroid, administ...