A major question in systems biology is how to identify the core gene regulatory circuit that governs the decision-making of a biological process. Here, we develop a computational platform, named NetAct, for constructing core transcription factor regulato
The top view of the core is shown on the left with the nine radial assembly rings labeled. Only the symmetric 1/12 segment inside the red lines is modeled. A horizontal slice of one assembly and an axial cross section of the optimized core configuration is shown on the right. Created usi...
This does not mean, however, that the perception of sustainability as an important issue has gained popularity only recently; in fact, it has been a focus of attention for a long time. Over 30 years ago, Meadows et al. (1972) warned that our future development is constrained by the growi...
Checks and balances are needed within the core executive to guard against the formulation of ill-advised policies through ‘groupthink’ or the abuse of power by one or a few powerful decision-makers. Where ‘policy fiascos’ occur the core executive must demonstrate a conce...
levels of their targeted genes, (2) identifying the regulatory interactions between two TFs based on their activi- ties rather than their expressions, and (3) subsequently simulating the constructed core GRN with RACIPE to validate and evaluate the gene expression dynamics of ...
Today, the pastoralists are the least integrated in the cash economy. This is partly due to a tradition of strong attachment to their lifestyle as well as a chronic absence of, or delayed and inadequate, interventions (e.g., schools, or employment generation schemes) in their territorial ...
There had also long been philosophers of asocial values, though not all of them applied this to their own lives. It was modernised and included many values from 1960s radicalism as Libertarianism, the core of the New Right. And it also hampers socialists and the liberal-left, since it was...
SG regions in S2, which mediated the interaction between the core and shell and thus provided indirect exchange coupling between the core and shell phases. The SAR values of the core-shell nanoparticles roughly agreed with the predictions of the linear response theory. The concentration of the nan...
In Section 2, a review of static and dynamic application mapping schemes—which can be considered HAM predecessors—is given and schemes for incremental design are presented. Section 3 provides an overview of the application and architecture models commonly used to describe the application mapping ...
Spatial division multiplexed optical transmission over a multi-ring-core orbital angular momentum (OAM) fibre is reported for the first time. The seven cores in the fibre each supports OAM modes belonging to mode groups (MGs) of topological charge | l |