Yoo J, Ha IC, Chang GT, Jung KS, Park K, Kim Y: CNVAS: Copy Number Variation Analysis System - the analysis tool for genomic alteration with a powerful visualization module. BioChip J 2011, 5(3):265-270.Yoo J, Ha IC, Chang GT, Jung KS, Park K, Kim Y. CNVAS: Copy Number ...
Feline mammary carcinomas (FMCs) are highly malignant. As the disease-free survival (DFS) and overall survival (OS) are short, prognostication is crucial. Copy-number variations (CNVs) analysis by next-generation sequencing serves to identify critical cancer-related genomic regions. Thirty-three fem...
Analysis of copy-number variation Copy-number variation (CNV) is a structural variation of the genome that may occur as (micro) deletions, duplications, or inversions, creating an anomalous number of copies of a DNA fragment. This variation may affect both the expression and the makeup of prot...
Epigenetic and Copy Number Variation Analysis in Retinoblastoma by MS-MLPA 喜欢 0 阅读量: 41 作者:Gabriella,Livide,Maria,Carmela,Epistolato,Mariangela,Amenduni,Vittoria,Disciglio,Annabella 摘要: Retinoblastoma is the most common primary intraocular malignancy in children. Two step inactivation of RB1 ...
In addition we have screened DNA from AC samples for chromosomal duplications or deletions using DNA microarray-based copy number variation analysis. Results The transcriptome consisting of 33096 gene probes showed a near-complete similarity in expression between AC and AM samples. Only nine genes ...
DNA copy number variants (CNVs) are found in 15% of subjects with ID but their association with phenotypic abnormalities has been predominantly studied in smaller cohorts of subjects with detailed yet non-systematically categorized phenotypes, or larger
Does not include up-front bioinformatic sequence analysis or in silico QC Human and mouse TaqMan Copy Number Reference Assays are also available. A simple method for studying study copy number variation, TaqMan Copy Number Assays fea...
copy number variant regions (CNVRs), covering 148.0 Mb (average of 44.1 kb) of polymorphic sequence. Among them, 2,124 “unique” (only present in one individual), 1,278 “gain” (account for 38.1%), 1,748 “loss” (52.1%) and 330 “both” (9.8%) were identified in our analysis...
Copy number variation (CNV) can drive rapid evolution in changing environments. In microbial pathogens, such adaptation is a key factor underpinning epidemics and colonization of new niches. However, the genomic determinants of such adaptation remain poo
This study describes the results of a large-scale case control analysis of copy number variants (CNVs) in a cohort of patients with congenital diaphragmatic hernia (CDH) and a large number of healthy population-matched controls. Using a customized array comparative genomic hybridization system, we ...