网络释义 1. 拷贝数变异 拷贝数变异(copy number variants)常用实验方法介绍Qing 微博 相关博文 精彩图文 推荐博文 谁看过这篇博文 加载中… blog.sina.com.cn|基于11个网页 2. 拷贝数量变异 这些"拷贝数量变异(copy number variants)" 的影响已经在高淀粉类饮食(high-starch diets)的族群中获得证实,他们比那 ...
Copy number variants (CNVs) are variants within the genome that arise from either duplication or deletion of a subset of an organism's genome. Within the human genome CNVs are now considered much more extensive than single nucleotide polymorphisms (SNPs) and are formed via a number of genomic ...
Copy number variation is a general term used to refer to population-level genetic differences characterized by the gain or loss of specific regions of DNA in individual genomes. Individual copy number variants (CNVs) may be inherited in the germline, or acquired as somatic mutations as in cancer...
Copy number variants (CNVs) are well-known and important risk factors for many conditions such as cancer1,2, schizophrenia3,4and autism5. High throughput sequencing (HTS) has been the standard technique for the detection of CNVs over the last decade. Various CNV detection algorithms that use w...
Tian M, Wang Y, Gu X, Feng C, Fang S, Hu X, Li N. Copy number variants in locally raised Chinese chicken genomes determined using array comparative genomic hybridization. BMC Genomics. 2013; 14 (1):262. doi: 10.1186/1471-2164-14-262. [ Cross Ref ]...
Abbreviations NDD: Neurodevelopmental disorders; ASD: Autism spectrum disorders; ID: Intellectual disability; iPSCs: Induced pluripotent stem cells; SNVs: Single nucleotide variants; CNVs: Copy number variants; WBS: Williams-Beuren syndrome; PMDS: Phelan-McDermid syndrome; miRNA: MicroRNA; lncRNA: ...
In the last years, in particular, new developments in genome-wide scanning methodologies have enabled the association of anumber of previously uncharacterized copy number variants (CNVs, gain or loss of DNA) in AD. Because of the exceedingly large number of studies performed, it has become ...
W. Glover, 2014 Copy number variants are produced in response to low-dose ionizing radiation in cultured cells. Environ. Mol. Mutagen. 55: 103-113.Arlt MF, Rajendran S, Birkeland SR, Wilson TE, Glover TW. Copy number variants are produced in response to low-dose ionizing radiation in ...
The contribution of germline copy number variants (CNVs) to risk of developing cancer in individuals with pathogenic BRCA1 or BRCA2 variants remains relatively unknown. We conducted the largest genome-wide analysis of CNVs in 15,342 BRCA1 and 10,740 BRCA
Human copy number variants (CNVs) account for genome variation an order of magnitude larger than single-nucleotide polymorphisms. Although much of this variation has no phenotypic consequences, some variants have been associated with disease, in particul