Cu is closely related to estrogen metabolism, and Cu toxicity in women is often found to be related to estrogen dominance. The aim of the present research work is to investigate the contribution of Cu in the initiation and progression of uterine leiomyomas (UL) and its influence on the ...
Copper reproductive toxicity. Copper pollution has become global environmental concern. Epidemiological research suggested that Cu exposure was related to women's reproductive toxicity. A single-center retrospective study showed that elevated Cu levels in serum is a risk factor for implantation failure (Ma...
Merono T, Dauteuille C, Tetzlaff W, Martin M, Botta E, Lhomme M, Saez MS, Sorroche P, Boero L, Arbelbide J, Chapman MJ, Kontush A, Brites F (2017) Oxidative stress, HDL functionality and effects of intravenous iron administration in women with iron deficiency anemia. Clin Nutr 36(...
Plasma AOs may be considered key enzymes in cell growth and differentiation processes and, thus, in tumor development and growth regulation. Moreover, the increased BzAO activity in blood serum of pregnant women supports the possibility that this enzyme has a protective role against the...
The copper IUD is a non-hormonal form of birth control which many women choose toavoid the risk of mood swings, anxietyand depression associated with hormonal contraceptives. Does copper increase estrogen? COPPER TOXICITY AND OTHER HEAVY METALS ...
Gram quantities of various copper salts have been taken in suicide attempts and produced acute copper toxicity in humans, possibly due to redox cycling and the generation of reactive oxygen species that damage DNA.[204][205] Corresponding amounts of copper salts (30 mg/kg) are toxic in animals...
Because copper has a role in these important tasks, it can help keep certain conditions at bay, such as: Anemia(low red blood cell count) Osteoporosis (boneloss, most often found in women) When You Don't Get Enough Your body doesn't need much copper, but when you're low, your health...
5l). According to ICP-MS data, HCT116 cells had higher Cu levels than DLD-1 cells, which correlated with the fluorescence intensity ratios in Fig. 3g. To determine if KRAS mutation and ATP7A upregulation correlates with a protective role against Cu toxicity, CRC cells were subjected to ...
Copper metabolism and cuproptosis are closely linked in the context of human diseases, with a particular focus on cancer. Cuproptosis refers to a specific type of copper-mediated cell death or copper toxicity triggered by disruptions in copper metabolism within the cells. This phenomenon encompasses...
Copper oxide nanoparticles (CuONPs) are widely used in a huge range of applications which might pose potential risk to organisms. Recent studies reported that CuONPs exposure resulted in transgenerational toxicity in Caenorhabditis elegans associated with possible epigenetic regulation. However, whether ...