Lamand, M Copper toxicity in sheep. In: Hermite, PL, Dehandtschutter, J, Reidel, D eds. (1981) Copper in animal wastes and sewage sludge. Reidel, Springer Netherlands, Dordrecht, pp. 261-272Lamand M. (1981) Copper toxicity in sheep. In: Copper in Animal Wastes and Sewage Sludge (...
In vivo toxicity of prion protein in murine scrapie: ultrastructural and immunogold studies Prion protein (PrP) is a cell surface, host coded, sialoglycoprotein which accumulates in excess in scrapie, Creutzfeldt‐Jakob disease, bovine spongiform ... M Jeffrey,CM Goodsir,ME Bruce,... - 《Neur...
Twelve housed yearling Swaledale sheep of normal copper status were given single subcutaneous injections of Cu Ca EDTA at doses ranging from 1·6 to 5 mg. Cu/kg. body weight. Two out of four given 3 mg. Cu/kg. and five given higher doses died within three days. Two had a haemolytic...
sheep failed to thrive, resulting in severe economic losses [6,7,8]. Cu deficiency includes direct and induced deficiencies. When ruminants have S and molybdenum (Mo) in the rumen, Cu will form poorly absorbed Cu-S-molybdate complexes with S and Mo. Then, induced Cu deficiency will occur....
Copper deficiencyin animals was first recognized in sheep in 1937, manifesting as anenzootic ataxia(also known as swayback), and subsequently was noted to affect other animals similarly.56,57Hematologic abnormalities were the first signs of acquiredcopper deficiencyrecognized in humans, withanemia,neutr...
Altogether, the Atp7b−/− mice represent a very useful and interesting model for analysis of copper toxicity in the liver. It is particularly important that marked morphological and biochemical changes, observed in these animals, can be directly linked to inactivation of a single gene, Atp7b...
copper oxide was dissolved in dilute sulfuric acid, concentrated and evaporated. category pesticide toxicity grade high toxicity Acute toxicity oral-rat LD50: 300 mg/kg storage and transportation characteristics warehouse ventilation and low-temperature drying; Separate from food storage and transporta...
Excess copper is bound by metallothioneins, which are upregulated to prevent toxicity. Copper is secreted into bile via a P-type ATPase (ATP7B), which is lacking in Wilson’s disease. Biliary excretion is the primary mode of homeostasis, and chronic copper toxicity is unlikely in the absence...
Acute copper toxicity results from ingestion of high copper feeds, copper salts, pesticides, poultry litter and other high copper substances. Acute copper poisoning can occur at copper intakes of 20-100 mg/kg in sheep and young calves, and 200-800 mg/kg in adult cattle. Chronic copper ...
Lamand, M Copper toxicity in sheep. In: Hermite, PL, Dehandtschutter, J, Reidel, D eds. (1981) Copper in animal wastes and sewage sludge. Reidel, Springer Netherlands, Dordrecht, pp. 261-272Lamand M. (1981) Copper toxicity in sheep. In: Copper in Animal Wastes and Sewage Sludge (...