These data, therefore, help explain why copper, in addition to being chemically more reactive, is more potent than iron at mediating LDL oxidation.doi:10.1074/jbc.270.10.5158Sean M. LynchBalz FreiJournal of Bio
Ascorbic acid can have both pro- and anti-oxidant roles, and it reacts with reactive oxygen species (ROS) and transition metals. Ascorbic acid can be readily oxidized by undergoing a one- or two-electron transfer, terminating the free radical-mediated chain reactions in foods and tissue, reduc...
It should be mentioned that everything has both sides. Iron and copper are beneficial to life in moderate amounts, but excesses or deficiencies of these metal ions are harmful. On the one hand, when there is too much iron in the body, excess iron forms a labile iron pool, confers cell ...
Copper(II) chloride is used as a mordant in dyeing and printing of fabrics; as an ingredient of isomerization and cracking catalysts; and as a desulfurizing and deodorizing agent in petroleum industry. Other important applications are in copper plating of aluminum; in tinting-baths for iron and...
Copper is an essential trace element for living organisms with many key roles in several metabolic pathways, including respiration, iron metabolism, antioxidant activity, tissue integrity and synaptic function. Cu can exist in two oxidation states Cu+ and Cu2+ in biological systems as it is charact...
Both are incompatible with magnesium, corrode steel and iron, may react with alkalis, phosphates, acetylene gas, hydrazine, or nitromethane, and may react with beta-naphthol, propylene glycol, sulphathiazole and triethanolamine if the pH exceeds 7 . Both act as acidic salts, corrode metals and ...
Among transition metal elements in brain, copper ranks third only to iron and zinc in pervasiveness. Yet, its disproportionation chemistry is unique due to its electronic structure (3s23p63d104s1) characterized by small energy differences between 3dand 4sorbitals that allows for strong hybridization ...
It is well known that metal-peroxo species are frequently capable of nucleophilic reactivity. Since it has been reported that the iron-hydroperoxo species is much more reactive than the corresponding iron-peroxo species in aldehyde deformylation40, the reactivity of1was further examined in the oxida...
Ferroptosis, a form of iron-dependent cell death triggered by lipid peroxidation and accumulation of lipid-based reactive oxygen species [118,119,120], appears to be influenced by copper levels due to the redox-active properties of copper ions [121,122]. Cuproptosis can modulate the expression ...
Copper ion, the third most abundant transition metal in the human body, plays a pivotal role in various physiological processes of organisms, such as haemopoiesis, iron absorption, and enzyme-catalysed and redox reactions [45,46]. Meanwhile, it can also catalyse the formation of reactive oxygen...