Copper (II) Ion Binding in Polyacrylic AcidThe complexing of Cu(II) by polyacrylic acid has been investigated. Potentiometric measurements have been employed to facilitate the experimental program. The stability constant of CuA2, the dominant species observed, has been determined to be approximately ...
网络释义 1. 铜离子结合 铜离子结合(copper ion binding) 60: abp1 afp alb aoc2 aoc3 aplp1 app apr-2 atox1 atp7a atp7b ccdc14 ccdc73 ccs cova1 cox… www.uscnk.cn|基于 1 个网页
Local atomic structure and oxidation processes of Cu(I) binding site in amyloid beta peptide: XAS Study Two or three histidine ligands can coordinate copper ion in varying conformations. On the other hand, oxidation of amyloid-β peptide could play an ... MA Kremennaya,MA Soldatov,VA Stretso...
The binding constant was 74,026 ± 2899 M−1 and the corresponding detection limit is found to be 9.6 ± 0.1 μM. It is interesting to note that upon EuL binding with Cu(II) ion, it became a selective responsive H2S probe. The detection limit was 2.7 ± 0.1 μM. The reversible ...
Essentially, no free Cu is available in eukaryotic cells since the ion is always complexed with other molecules. Small molecules such as GSH and metallothioneins bind Cu for storage and/or detoxification and may provide an exchangeable pool of Cu. Furthermore, proteins called metallochaperones ...
using copper as our model ion of interest and inspired by nature’s use of histidine residues within the active sites of various copper binding proteins, we design a framework featuring pendant imidazole rings and copper-chelating salicylaldoxime, known as zinc imidazole salicylaldoxime supramolecule....
In a standard experiment, the reconstituted protein was incubated with increasing concentrations of copper chelators for 1 min and samples were injected into the electrospray ion source of an Agilent Technology 6540 UHD Accurate-Mass Q-TOF MS instrument (Agilent) by a syringe pump at 7 μL...
Further research is needed to resolve these contradictions. Structural biology approaches, in general, and NMR spectroscopy, in particular, have the potential to be very useful in the study of copper ion coordination with PrP to help elucidate the role played by copper ions in prion diseases [...
respectively. TheQmvalues of SDA were to some extent greater than those of SSD and SD owing to the possible higher main FGs in the structure of SDA biochar. Hence, SDA biochar had extra binding active spots and more negative surfaces, thus improving Cu(II) ion retentions on the surface of...
Here, we describe the structure of a C-terminal high-affinity copper-binding site within a truncated recombinant human PrP containing residues 91–231, which lacks the octapeptide repeat region. We show that at least two extra co-ordinating groups are involved in binding this copper(II) ion in...