Lung volumes in COPD: not only the total lung capacity.Obstructive sleep apneaAnimal modelAirway obstructionInflammationComment on Chest. 2010 May;137(5):1108-15. Chest. 1999 Jan;115(1):68-74.doi:10.1378/chest.10-0045Scarlata, Simone
Errors in the measurement of total lung capacity in chronic obstructive lung disease. The standard plethysmographic method of measuring total lung capacity (TLC) has been reported to result in spuriously high estimates in patients with severe airway obstruction. The helium-dilution method is known to...
Methods: Subjects (n=1,050) aged 50-64 years were investigated with FEV1, FVC, and SVC after bronchodilation. Global Initiative for Chronic Obstructive Lung Disease (GOLD) COPDFVC was defined as FEV1/FVC VC as FEV1/VC FVC as FEV1/FVC below the LLN, and LLNCOPDVC as FEV1/VC below the...
建议用药前完善血常规、血生化、胸部CT和肺功能检测,关注FEV1、FVC、一氧化碳弥散量(diffusing lung capacity for carbon monoxide, DLCO)等肺功能指标,白细胞计数、中性粒细胞计数与占比、降钙素原(procalcitonin, PCT)等感染指标,以及白...
The formal diagnosis of COPD is made with spirometry; when the ratio of forced expiratory volume in 1 second over forced vital capacity (FEV1/FVC) is less than 70% of that predicted for a matched control, it is diagnostic for a significant obstructive defect. Criteria for assessing the severi...
‘spirometry’, and this can be arranged by GPs. Spirometry involves blowing hard and fast into a machine that measures an individual’s lung functioning and capacity. However, spirometry only covers one aspect of an individual’s lung function. Individuals with the same test result may be more...
Objective: To investigate the correlation between the serum hypoxia-inducible factor-1伪, uric acid, inflammatory factor levels, and lung function in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Met... S Deng,T Zhu,Cen WangXinnan GuJun ZhangQin LuYan YangXi...
The inclusion criterion of the first study was patients aged 40 years and above with the ratio of post-bronchodilator FEV1 (PB-FEV1) to post-bronchodilator forced vital capacity (PB-FVC) of < 0.7; while the inclusion criterion for the second study was patients aged 35 years and above ...
breaths become increasingly shallow and end-expiratory lung volume progressively enlarges (Panel A, normal response to exercise; Panel B, response with COPD). This phenomenon is called dynamic hyperinflation and is thought to b...
Furthermore, the area under the MEFV curve has been correlated with RV/total lung capacity (TLC), a common index of air trapping42 as well as exercise capacity in COPD patients43. Moreover, the Obstructive Index, defined as a ratio of FVC to the volume-difference between two points of ha...