1-antitrypsin deficiency* 4: molecular pathophysiology. Thorax. 2004;59(6):529–535. doi:10.1136/thx.2003.006528 32. Yao J, Guihard PJ, Blazquez-Medela AM, et al. Serine protease activation essential for endothelial-mesenchymal transition in vascular calcification. Circ Res....
COPD (especially the emphysema sub-type) and periodontitis are believed to share a similar pathophysiology, namely inflammation and the destruction of the local connective tissue. There is evidence that the neutrophil is a key cell in the inflammatory response to both diseases, and that its protease...
Pulmonary hypertension (PH) in patients with chronic obstructive pulmonary disease (COPD) is associated with an increase in the risk of COPD exacerbation, increased hospitalization, and worse survival in this patient population. No specific treatment is
GHK was first studied for wound healing (1983+) and later for its effects on skin and hair. In many controlled, peer-reviewed published articles, GHK was found to: •Tightened loose skinand thicken older skin •Repaired protective skin barrier proteins ...
Furthermore, the application of new technologies that investigate the functional role of macrophages and, in particular, the combination of cell types as well as single-cell transcriptomics and proteomic approaches, are creating new opportunities to understand and clarify the pathophy...
However, as shown in this study, the knowledge base of community pharmacists in China was inadequate to support their practice and weaknesses in the knowledge about the etiology, pathophysiology, pharmacotherapy, and non-pharmacotherapy were prominent. Their overall knowledge level abou...